Hawkar Ibrahim Ahmed, Ebru Bozkurt, Muhammet Yildirim, Akın Sağırlı
{"title":"New Styryl 1,3,4-Oxadiazol-Based Fluorometric \"Turn on\" pH Sensor.","authors":"Hawkar Ibrahim Ahmed, Ebru Bozkurt, Muhammet Yildirim, Akın Sağırlı","doi":"10.1007/s10895-024-04036-6","DOIUrl":null,"url":null,"abstract":"<p><p>A new 1,3,4-oxadiazole derivative (MeO-SODA) was synthesized, fully characterized by means of IR, NMR and HRMS data and and additionally, its ability to detect extremely acidic pH values was examined. Firstly, the characteristic behavior of MeO-SODA was examined in ten different solvents, revealing that it underwent non-radiative transitions as the hydrogen bonding capacity of solvent increased. Secondly, the absorption and fluorescence measurements for MeO-SODA were conducted across various pH levels (pH 2, 4, 6, 7, 9, 10, 12), with fluorescence emission observed exclusively at pH 2. We propose that this new probe could serve as a highly selective sensor at extremely acidic pH levels. Additionally, experiments with lemon juice demonstrated that this new 1,3,4-oxadiazole derivative could be suitable for practical applications. Furthermore, the results of this study are expected to provide insights into synthesizing new probes capable of detecting at a single pH value, setting them apart from the typical pH studies found in the literature.</p>","PeriodicalId":15800,"journal":{"name":"Journal of Fluorescence","volume":" ","pages":""},"PeriodicalIF":2.6000,"publicationDate":"2024-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Fluorescence","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.1007/s10895-024-04036-6","RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"BIOCHEMICAL RESEARCH METHODS","Score":null,"Total":0}
引用次数: 0
Abstract
A new 1,3,4-oxadiazole derivative (MeO-SODA) was synthesized, fully characterized by means of IR, NMR and HRMS data and and additionally, its ability to detect extremely acidic pH values was examined. Firstly, the characteristic behavior of MeO-SODA was examined in ten different solvents, revealing that it underwent non-radiative transitions as the hydrogen bonding capacity of solvent increased. Secondly, the absorption and fluorescence measurements for MeO-SODA were conducted across various pH levels (pH 2, 4, 6, 7, 9, 10, 12), with fluorescence emission observed exclusively at pH 2. We propose that this new probe could serve as a highly selective sensor at extremely acidic pH levels. Additionally, experiments with lemon juice demonstrated that this new 1,3,4-oxadiazole derivative could be suitable for practical applications. Furthermore, the results of this study are expected to provide insights into synthesizing new probes capable of detecting at a single pH value, setting them apart from the typical pH studies found in the literature.
期刊介绍：
Journal of Fluorescence is an international forum for the publication of peer-reviewed original articles that advance the practice of this established spectroscopic technique. Topics covered include advances in theory/and or data analysis, studies of the photophysics of aromatic molecules, solvent, and environmental effects, development of stationary or time-resolved measurements, advances in fluorescence microscopy, imaging, photobleaching/recovery measurements, and/or phosphorescence for studies of cell biology, chemical biology and the advanced uses of fluorescence in flow cytometry/analysis, immunology, high throughput screening/drug discovery, DNA sequencing/arrays, genomics and proteomics. Typical applications might include studies of macromolecular dynamics and conformation, intracellular chemistry, and gene expression. The journal also publishes papers that describe the synthesis and characterization of new fluorophores, particularly those displaying unique sensitivities and/or optical properties. In addition to original articles, the Journal also publishes reviews, rapid communications, short communications, letters to the editor, topical news articles, and technical and design notes.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
