Beyond static measurements: dynamic frailty improves survival prediction in multiple myeloma.

IF 21 1区医学 Q1 HEMATOLOGY

Blood Pub Date : 2024-11-22 DOI:10.1182/blood.2024025868

F Smits, Kaz Groen, Mark-David Levin, Claudia Stege, Roel J W van Kampen, Ellen van der Spek, Yavuz M Bilgin, Noortje Thielen, Inger S Nijhof, Inge Ludwig, Esther G M de Waal, Yorick Sandberg, Alain Kentos, Gert-Jan Timmers, Josien C Regelink, Matthijs Westerman, Koen de Heer, Marie-Christiane Mb Vekemans, Nazik Durdu-Rayman, Nicole C H P de Graauw, Maarten R Seefat, Niels W C J van de Donk, Paula F Ypma, Kazem Nasserinejad, Sonja Zweegman

引用次数: 0

Abstract

The level of frailty, according to the IMWG frailty index, is highly dynamic during anti-myeloma treatment. Dynamic frailty assessment improved the prediction of survival and early mortality as compared to the prognostic value of static frailty level at baseline. HOVON 143: NTR6297 HOVON 123: NTR4244.

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超越静态测量：动态虚弱度可改善多发性骨髓瘤的生存预测。

根据IMWG虚弱指数，虚弱程度在抗骨髓瘤治疗期间是高度动态的。与基线静态虚弱水平的预后价值相比，动态虚弱评估提高了对生存率和早期死亡率的预测。HOVON 143: NTR6297 HOVON 123：NTR4244.

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Blood 医学-血液学

CiteScore

23.60

自引率

3.90%

发文量

955

审稿时长

1 months

期刊介绍： Blood, the official journal of the American Society of Hematology, published online and in print, provides an international forum for the publication of original articles describing basic laboratory, translational, and clinical investigations in hematology. Primary research articles will be published under the following scientific categories: Clinical Trials and Observations; Gene Therapy; Hematopoiesis and Stem Cells; Immunobiology and Immunotherapy scope; Myeloid Neoplasia; Lymphoid Neoplasia; Phagocytes, Granulocytes and Myelopoiesis; Platelets and Thrombopoiesis; Red Cells, Iron and Erythropoiesis; Thrombosis and Hemostasis; Transfusion Medicine; Transplantation; and Vascular Biology. Papers can be listed under more than one category as appropriate.