Anuradha Chowdhary, Gaston I. Jofre, Ashutosh Singh, Andrius J. Dagilis, Victoria E. Sepúlveda, Allison T McClure, Daniel R. Matute
{"title":"Autochthonous Blastomyces dermatitidis, India","authors":"Anuradha Chowdhary, Gaston I. Jofre, Ashutosh Singh, Andrius J. Dagilis, Victoria E. Sepúlveda, Allison T McClure, Daniel R. Matute","doi":"10.3201/eid3012.240830","DOIUrl":null,"url":null,"abstract":"<p><em>Blastomyces</em> spp. fungi, the causal agent of blastomycosis, are common in North America but do occur in other areas of the world. The most prevalent pathogen in the genus is <em>B. dermatitidis</em>. Most<em> B. dermatitidis</em> isolates originate from North America, but there are sporadic reports of <em>B. dermatitidis</em> recovery from Africa and Asia. High-quality reports that incorporate genetic information about the fungus outside North America have been rare. Genome sequencing of 3 fungal isolates from patients in India with chronic respiratory diseases revealed that the isolates belong to a genetically differentiated lineage of <em>B. dermatitidis</em>. Because the patients had no history of traveling outside of Asia, blastomycosis was most likely autochthonously acquired, which suggests a local population of <em>B. dermatitidis</em>. Our results suggest the endemic range of <em>B. dermatitidis</em> is larger than previously thought, calling for a reassessment of the geographic range of different agents of endemic mycoses.</p>","PeriodicalId":11595,"journal":{"name":"Emerging Infectious Diseases","volume":"116 1-2 1","pages":""},"PeriodicalIF":7.2000,"publicationDate":"2024-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Emerging Infectious Diseases","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.3201/eid3012.240830","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"IMMUNOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Blastomyces spp. fungi, the causal agent of blastomycosis, are common in North America but do occur in other areas of the world. The most prevalent pathogen in the genus is B. dermatitidis. Most B. dermatitidis isolates originate from North America, but there are sporadic reports of B. dermatitidis recovery from Africa and Asia. High-quality reports that incorporate genetic information about the fungus outside North America have been rare. Genome sequencing of 3 fungal isolates from patients in India with chronic respiratory diseases revealed that the isolates belong to a genetically differentiated lineage of B. dermatitidis. Because the patients had no history of traveling outside of Asia, blastomycosis was most likely autochthonously acquired, which suggests a local population of B. dermatitidis. Our results suggest the endemic range of B. dermatitidis is larger than previously thought, calling for a reassessment of the geographic range of different agents of endemic mycoses.
期刊介绍：
Emerging Infectious Diseases is a monthly open access journal published by the Centers for Disease Control and Prevention. The primary goal of this peer-reviewed journal is to advance the global recognition of both new and reemerging infectious diseases, while also enhancing our understanding of the underlying factors that contribute to disease emergence, prevention, and elimination.
Targeted towards professionals in the field of infectious diseases and related sciences, the journal encourages diverse contributions from experts in academic research, industry, clinical practice, public health, as well as specialists in economics, social sciences, and other relevant disciplines. By fostering a collaborative approach, Emerging Infectious Diseases aims to facilitate interdisciplinary dialogue and address the multifaceted challenges posed by infectious diseases.
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