The Efficacy for Hypertensive Intracerebral Hemorrhage Between Neuroendoscopic Surgery and Conservative Treatment: A Retrospective Observational Study.

IF 1.1 4区医学 Q4 CLINICAL NEUROLOGY

Neurologist Pub Date : 2024-11-21 DOI:10.1097/NRL.0000000000000597

Guojin Huo, Yanping Lan, Yi Feng, Xiang Gao, Chen Chen

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引用次数: 0

Abstract

Objectives: This study aims to investigate the efficacy of neuroendoscopic surgery in the treatment of hypertensive intracerebral hemorrhage (HICH).

Methods: A total of 193 patients diagnosed with HICH were divided into 2 groups in this study: the observation group (n=101) received neuroendoscopic surgery, whereas the control group (n=92) underwent conservative treatment. Then, the outcomes between these 2 groups were compared and assessed.

Results: In the pretreatment phase, there were no significant differences in the levels of inflammation and neurological function scores between these 2 groups (P>0.05). After 3 months of treatment, the observation group displayed significantly shorter median hospital stay, lower average hospital costs, and faster hematoma resorption time, along with reduced levels of tumor necrosis factor-alpha (TNF-α), C-reactive protein (CRP), interleukin (IL)-6 and IL-8, aquaporin-4 (AQP4), macrophage migration inhibitory factor (MIF), matrix metalloproteinase-9 (MMP-9), granulocyte macrophage colony stimulating factor (GM-CSF), Nerve Deficiency Scale (NDS), Graeb score, and national institute of health stroke scale (NIHSS) compared with the control group (P<0.05). In addition, the observation group exhibited higher rate of hematoma clearance and better glasgow outcome scale (GOS) score compared with the control group (P<0.05). The effective treatment rate in the observation group was notably superior to that in the control group (89.11% vs. 73.91%, P<0.05).

Conclusions: Neuroendoscopic surgery is an effective treatment for HICH, with alleviating the inflammatory response and enhancing the neurological function. The treatment shows promising outcomes and justifies extensive implementation.

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神经内镜手术与保守治疗对高血压性脑出血的疗效：一项回顾性观察研究。

目的：本研究旨在探讨神经内镜手术治疗高血压性脑出血（HICH）的疗效：本研究旨在探讨神经内镜手术治疗高血压性脑出血（HICH）的疗效：方法：将193例确诊为HICH的患者分为两组：观察组（101例）接受神经内镜手术治疗，对照组（92例）接受保守治疗。然后对两组患者的治疗效果进行比较和评估：在治疗前，两组患者的炎症水平和神经功能评分无明显差异（P>0.05）。治疗 3 个月后，观察组的中位住院时间明显缩短，平均住院费用降低，血肿吸收时间加快，肿瘤坏死因子-α（TNF-α）、C 反应蛋白（CRP）、白细胞介素（IL）-6 和 IL-8 水平降低、与对照组（PConclusions：神经内镜手术是治疗 HICH 的有效方法，可减轻炎症反应，增强神经功能。这种治疗方法显示出良好的疗效，值得广泛推广。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Neurologist 医学-临床神经学

CiteScore

1.90

自引率

0.00%

发文量

151

审稿时长

2 months

期刊介绍： The Neurologist publishes articles on topics of current interest to physicians treating patients with neurological diseases. The core of the journal is review articles focusing on clinically relevant issues. The journal also publishes case reports or case series which review the literature and put observations in perspective, as well as letters to the editor. Special features include the popular "10 Most Commonly Asked Questions" and the "Patient and Family Fact Sheet," a handy tear-out page that can be copied to hand out to patients and their caregivers.