Ymke J Evers, Charlotte Mm Peters, Petra Fg Wolffs, Dieuwertje L Horsten, Chantal Weijzen, Nicole Htm Dukers-Muijrers, Christian Jpa Hoebe
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引用次数: 0
Abstract
Background: Female sex workers (FSW) have a higher burden of sexually transmitted infections (STI), including Neisseria gonorrhoeae (NG), than the non-sex worker population, mainly due to social vulnerability and work-related factors. This large study evaluated the anatomical site distribution of NG, and specifically the occurrence of single-site pharyngeal NG, among FSW visiting Dutch STI clinics in the Netherlands.
Methods: Coded STI clinic consultations from FSW attending any Dutch STI clinic between 2016 and 2021, in which tests were performed on all three anatomical sites, according to the Dutch testing policy for FSW, were included in analyses (n = 22,304). To compare the anatomical site distribution of NG among FSW with women in general, 15,494 consultations from women who were tested on three anatomical sites in clinics that performed standard testing at three anatomical sites were used. Descriptive statistics were used to compare the anatomical site distribution of NG and occurrence of single-site pharyngeal NG among FSW and universally tested women.
Results: NG was diagnosed among 3.5% (782/22,034) among FSW and 1.7% (271/15,494) among universally tested women (p < 0.001). Pharyngeal NG was diagnosed among 2.3% among FSW, versus 0.8% among universally tested women (p < 0.001). Single-site pharyngeal NG was diagnosed in 19.9% (156/782) of all NG infections, compared to 14.8% (40/271) of NG infections among universally tested women.
Conclusion: The substantial proportion pharyngeal NG and single-site pharyngeal NG among FSW, confirms the relevance of pharyngeal testing among this key population for optimal patient management, also in the context of the potential role of pharyngeal NG in antimicrobial resistance.
背景：与非性工作者人群相比，女性性工作者（FSW）感染性传播疾病（STI）（包括淋病奈瑟菌（NG））的几率更高，这主要是由于社会脆弱性和工作相关因素造成的。这项大型研究评估了 NG 的解剖部位分布情况，特别是在荷兰性传播感染诊所就诊的 FSW 中，单部位咽部 NG 的发生情况：分析对象包括2016年至2021年期间在荷兰任何一家性传播疾病诊所就诊的女性同性恋者，根据荷兰针对女性同性恋者的检测政策，在所有三个解剖部位进行了检测（n = 22304）。为了比较女性同性恋者与一般女性的 NG 解剖部位分布情况，我们使用了 15,494 名女性咨询者的数据，这些咨询者在诊所接受了三个解剖部位的检测，诊所在三个解剖部位进行了标准检测。采用描述性统计方法比较了女性外阴残留物的解剖部位分布情况，以及女性外阴残留物在女性外阴残留物感染者和接受普遍检测的女性中单个部位咽部残留物的发生情况：结果：3.5%（782/22,034）的女性外阴残割者被诊断出患有鼻咽癌，1.7%（271/15,494）的普遍受检女性被诊断出患有鼻咽癌（P < 0.001）。咽部 NG 的确诊率为 2.3%，而在接受普遍检测的女性中为 0.8%（P < 0.001）。在所有咽部 NG 感染中，19.9%（156/782）被诊断为单部位咽部 NG，而在接受全面检测的女性中，14.8%（40/271）被诊断为单部位咽部 NG：结论：咽部 NG 和单部位咽部 NG 在女性外阴残割者中的比例很高，这证实了在这一关键人群中进行咽部检测对优化患者管理的重要性，同时也说明了咽部 NG 在抗菌药耐药性中的潜在作用。
期刊介绍：
Sexually Transmitted Diseases, the official journal of the American Sexually Transmitted Diseases Association, publishes peer-reviewed, original articles on clinical, laboratory, immunologic, epidemiologic, behavioral, public health, and historical topics pertaining to sexually transmitted diseases and related fields. Reports from the CDC and NIH provide up-to-the-minute information. A highly respected editorial board is composed of prominent scientists who are leaders in this rapidly changing field. Included in each issue are studies and developments from around the world.
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