Inspired by an ancient Chinese Medicine prescription: the modern significance and potential of Yiyi Fuzi Baijiang San in treating diseases.

IF 4.4 2区医学 Q1 PHARMACOLOGY & PHARMACY

Frontiers in Pharmacology Pub Date : 2024-11-07 eCollection Date: 2024-01-01 DOI:10.3389/fphar.2024.1465387

Yuli Zhang, Lu Zhang, Ni Chai, ZhiQiang Wan, Hua Sui

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Abstract

Classic Formulas (Jing fang) are considered the essence and authority of Traditional Chinese Medicine (TCM) due to their long history and proven efficacy. These formulas play a pivotal role in all kinds of different disease prevention and therapeutic strategies. Yiyi Fuzi Baijiang San (YYFZBJS), one of the Classic Formulas, was originally developed for the treatment of chronic intestinal abscess. With the accumulation of clinical experience and the exploration of modern pharmacological research in recent years, YYFZBJS has been extensively employed to address a broad spectrum of conditions such as colorectal cancer. Although numerous studies have explored the clinical efficacy and underlying mechanisms of YYFZBJS, no comprehensive review summarizing these findings exists to date. This study aims to systematically review and critically assess the current clinical and mechanistic research on YYFZBJS, with the objective of providing valuable insights and guidance for TCM research in the future.

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从中医古方中汲取灵感：一味附子白江散治疗疾病的现代意义和潜力。

经典方剂（经方）因其悠久的历史和公认的疗效而被视为传统中医药（TCM）的精髓和权威。这些方剂在各种不同疾病的预防和治疗策略中发挥着举足轻重的作用。经典方剂之一的 "益母草白江散 "最初是为治疗慢性肠脓肿而研制的。近年来，随着临床经验的积累和现代药理研究的探索，逍遥散已被广泛用于治疗结直肠癌等多种疾病。尽管已有大量研究探讨了 YYFZBJS 的临床疗效和内在机制，但迄今为止还没有综述这些研究结果的全面综述。本研究旨在系统回顾和批判性评估目前有关养阴清热汤的临床和机理研究，以期为未来的中医药研究提供有价值的见解和指导。

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来源期刊

Frontiers in Pharmacology PHARMACOLOGY & PHARMACY-

CiteScore

7.80

自引率

8.90%

发文量

5163

审稿时长

14 weeks

期刊介绍： Frontiers in Pharmacology is a leading journal in its field, publishing rigorously peer-reviewed research across disciplines, including basic and clinical pharmacology, medicinal chemistry, pharmacy and toxicology. Field Chief Editor Heike Wulff at UC Davis is supported by an outstanding Editorial Board of international researchers. This multidisciplinary open-access journal is at the forefront of disseminating and communicating scientific knowledge and impactful discoveries to researchers, academics, clinicians and the public worldwide.