Functional precision medicine: the future of cancer care.

IF 12.8 1区医学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY

Trends in molecular medicine Pub Date : 2024-11-19 DOI:10.1016/j.molmed.2024.10.015

Arlet M Acanda de la Rocha, Noah E Berlow, Diana J Azzam

引用次数: 0

Abstract

Functional precision medicine (FPM), combining ex vivo drug sensitivity testing with genomic profiling to identify treatment options for recurrent/refractory cancer, is feasible and poised to accelerate. This forum explores the history of FPM, recent clinical advancements, and barriers to expanding the clinical utility and accessibility for pediatric/adolescent and adult cancers.

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功能性精准医疗：癌症治疗的未来。

功能性精准医疗（FPM）将体内外药物敏感性测试与基因组图谱分析相结合，以确定复发/难治性癌症的治疗方案，这是可行的，而且有望加速发展。本论坛将探讨功能精准医学的历史、最新临床进展以及扩大临床应用和儿童/青少年及成人癌症治疗可及性的障碍。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Trends in molecular medicine 医学-生化与分子生物学

CiteScore

24.60

自引率

0.00%

发文量

142

审稿时长

6-12 weeks

期刊介绍： Trends in Molecular Medicine (TMM) aims to offer concise and contextualized perspectives on the latest research advancing biomedical science toward better diagnosis, treatment, and prevention of human diseases. It focuses on research at the intersection of basic biology and clinical research, covering new concepts in human biology and pathology with clear implications for diagnostics and therapy. TMM reviews bridge the gap between bench and bedside, discussing research from preclinical studies to patient-enrolled trials. The major themes include disease mechanisms, tools and technologies, diagnostics, and therapeutics, with a preference for articles relevant to multiple themes. TMM serves as a platform for discussion, pushing traditional boundaries and fostering collaboration between scientists and clinicians. The journal seeks to publish provocative and authoritative articles that are also accessible to a broad audience, inspiring new directions in molecular medicine to enhance human health.