[Translated article] Psoriatic Patient-Reported Outcomes, Adherence, and Satisfaction.

IF 3.8 Q1 DERMATOLOGY

Actas dermo-sifiliograficas Pub Date : 2024-11-19 DOI:10.1016/j.ad.2024.11.015

J Perales Pascual, H Navarro Aznárez, A López Pérez, T Gracia-Cazaña, Y Gilaberte Calzada, Mª R Abad Sazatornil

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引用次数: 0

Abstract

Background: Patient-reported outcomes (PROs) are outcomes evaluated by patients based on their perception of their disease and treatment.

Objectives: Determine antipsoriatic treatment-related adherence, quality of life (QoL) and satisfaction.

Materials and methods: We conducted an observational cross-sectional, prospective, and single-center study in which PROs surveys were conducted on adherence (Morisky-Green [MG] test), treatment satisfaction (Spanish Questionnaire of Treatment Satisfaction in Psoriasis [CESTEP]) and QoL (Skindex-29 and DLQI). Additional variables include: PASI, BSA.

Statistical analysis: Jamovi®2.3.26.

Results: A total of 100 surveys were conducted. Based on the MG questionnaire, we found that 75% (75/100) of patients were adherent vs 94% (94/100) from the dispensation records. Regarding CESTEP, a mean score of 7.4±7.7 (close to maximum satisfaction 0) was obtained, while DLQI yielded a score of 2.6±4.6 (indicating a small effect on QoL), and SKINDEX-29 a score of 14.6±15.4 (68% indicating mild (<5) or very mild (6-17) impact according to Nijsten et al.). Based on CESTEP a p.Rho Spearman value of 0.338 (p=0.004) was obtained in relation to PASI when the study was conducted with a BSA of 0.255 (p=0.050), DLQI results of 0.508 (p<0.001) and Skindex-29 results of 0.397(p<0.001). At the time of the study, the correlation matrix between DLQI result and PASI was 0.365 (p=0.002) with a BSA of 0.347 (p=0.007). Skindex-29 results with PASI were 0.380 (p=0.001) and with BSA, 0.295 (p=0.022).

Conclusions: Patients on therapy exhibit a good QoL, high adherence and satisfaction with their treatment. A significant correlation was seen among satisfaction, QoL, and PASI-BSA at the time of the study.

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银屑病患者的患者报告结果、依从性和满意度。

背景和目的：患者报告的结果（PROs）是患者根据自己对疾病和治疗的感知进行评估的结果。PROs的目的是确定与抗银屑病治疗相关的依从性、生活质量（QoL）和满意度：我们进行了一项观察性横断面、前瞻性和单中心研究，对患者的依从性（莫里斯基-格林[MG]测试）、治疗满意度（西班牙银屑病治疗满意度问卷[CESTEP]）和生活质量（Skindex-29 和 DLQI）进行了 PROs 调查。其他变量包括统计分析：统计分析：Jamovi®2.3.26：共进行了 100 次调查。根据 MG 问卷，我们发现 75% （75/100）的患者坚持用药，而根据配药记录，坚持用药的患者比例为 94%（94/100）。关于 CESTEP，平均得分为 7.4 ± 7.7（接近最高满意度 0），而 DLQI 得分为 2.6 ± 4.6（表明对 QoL 的影响较小），SKINDEX-29 得分为 14.6 ± 15.4（根据 Nijsten 等人的研究，68% 表明影响轻微（< 5）或非常轻微（6-17））。根据 CESTEP，在进行 BSA 为 0.255（p = 0.050）、DLQI 为 0.508（p < 0.001）和 Skindex-29 为 0.397（p < 0.001）的研究时，PASI 的 p.Rho Spearman 值为 0.338（p = 0.004）。在研究期间，DLQI 结果与 PASI 之间的相关矩阵为 0.365（p = 0.002），BSA 为 0.347（p = 0.007）。Skindex-29结果与PASI的相关系数为0.380（p = 0.001），与BSA的相关系数为0.295（p = 0.022）：结论：接受治疗的患者表现出良好的生活质量、较高的依从性和对治疗的满意度。结论：接受治疗的患者表现出良好的生活质量、较高的依从性和对治疗的满意度。在研究期间，满意度、生活质量和 PASI-BSA 之间存在明显的相关性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Actas dermo-sifiliograficas DERMATOLOGY-

CiteScore

1.90

自引率

9.40%

发文量

473

审稿时长

56 weeks

期刊介绍： Actas Dermo-Sifiliográficas, publicación Oficial de la Academia Española de Dermatología y Venereología, es una revista de prestigio consolidado. Creada en 1909, es la revista mensual más antigua editada en España.En 2006 entró en Medline, y hoy resulta imprescindible para estar al día sobre la dermatología española y mundial.