Relationship between nerve ultrasonography image and electrophysiology in diabetic polyneuropathy.

IF 3.2 3区医学

Journal of Diabetes Investigation Pub Date : 2024-11-21 DOI:10.1111/jdi.14353

Pei-Chen Hsieh, Long-Sun Ro, Chun-Che Chu, Ming-Feng Liao, Hong-Shiu Chang, Hung-Chou Kuo

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Abstract

Aims/introduction: This study aims to investigate the association between cross-sectional area (CSA) imaging findings of nerve ultrasound and conventional nerve conduction studies (NCS) for patients with distal symmetric sensorimotor polyneuropathy (DSPN) due to type 2 diabetes mellitus.

Materials and methods: We enrolled 103 patients with type 2 diabetes mellitus and collected their demographic data, modified Michigan Neuropathy Screening Instrument (mMNSI) score, NCS, and ultrasonography images of peripheral nerves. The relationship of ultrasound variables for individual nerves and the ultrasound pattern sum score (UPSS) to conventional NCS findings was investigated.

Results: A higher grade of DSPN was associated with a notably higher CSA. Multivariate step-wise regression analysis revealed that the number of abnormal nerves was a positive independent variable for UPSS (β coefficient = 0.4205; P < 0.0001). Of the five nerves studied, abnormalities of the tibial nerve (P ≤ 0.0100) and ulnar nerve (P = 0.052) were the most significant variables.

Conclusions: The tibial nerve exhibited the most substantial association with elevated UPSS. In addition, a strong correlation was observed between abnormal NCS findings and UPSS in patients with DSPN.

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糖尿病多发性神经病变中神经超声图像与电生理学之间的关系

目的/简介：本研究旨在探讨 2 型糖尿病导致的远端对称性感觉运动性多发性神经病（DSPN）患者的神经超声横截面积（CSA）成像结果与常规神经传导研究（NCS）之间的关联：我们招募了103名2型糖尿病患者，收集了他们的人口统计学数据、改良密歇根神经病变筛查工具（mMNSI）评分、NCS和外周神经超声图像。研究了单个神经的超声变量和超声模式总分（UPSS）与传统 NCS 结果的关系：结果：DSPN等级越高，CSA明显越高。多变量逐步回归分析表明，异常神经的数量是 UPSS 的一个正向自变量（β 系数 = 0.4205；P 结论：胫神经表现出最明显的畸形，而腓肠肌则表现出最明显的畸形：胫神经与 UPSS 升高的关系最为密切。此外，在 DSPN 患者中，异常 NCS 结果与 UPSS 之间存在很强的相关性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Diabetes Investigation Medicine-Internal Medicine

自引率

9.40%

发文量

218

期刊介绍： Journal of Diabetes Investigation is your core diabetes journal from Asia; the official journal of the Asian Association for the Study of Diabetes (AASD). The journal publishes original research, country reports, commentaries, reviews, mini-reviews, case reports, letters, as well as editorials and news. Embracing clinical and experimental research in diabetes and related areas, the Journal of Diabetes Investigation includes aspects of prevention, treatment, as well as molecular aspects and pathophysiology. Translational research focused on the exchange of ideas between clinicians and researchers is also welcome. Journal of Diabetes Investigation is indexed by Science Citation Index Expanded (SCIE).