Shining light to break planarity

IF 42.8 1区化学 Q1 CHEMISTRY, PHYSICAL

Nature Catalysis Pub Date : 2024-11-21 DOI:10.1038/s41929-024-01254-w

Ricardo J. Fernández-Terán

引用次数: 0

Abstract

The synthesis of rigid C(sp3)-rich isosteric mimics of heteroaromatic rings has proved a significant challenge, but is of importance in drug discovery. Now, two studies report the synthesis of densely functionalized azetidines and bicycloalkanes, using a similar concept of breaking planarity.

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闪耀的光芒打破平面性

事实证明，合成富含 C(sp3)的杂芳香环的刚性异构模拟物是一项重大挑战，但在药物发现方面却具有重要意义。现在，两项研究报告了利用类似的打破平面性概念合成致密官能化氮杂环丁烷和双环烷的过程。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Nature Catalysis Chemical Engineering-Bioengineering

CiteScore

52.10

自引率

1.10%

发文量

140

期刊介绍： Nature Catalysis serves as a platform for researchers across chemistry and related fields, focusing on homogeneous catalysis, heterogeneous catalysis, and biocatalysts, encompassing both fundamental and applied studies. With a particular emphasis on advancing sustainable industries and processes, the journal provides comprehensive coverage of catalysis research, appealing to scientists, engineers, and researchers in academia and industry. Maintaining the high standards of the Nature brand, Nature Catalysis boasts a dedicated team of professional editors, rigorous peer-review processes, and swift publication times, ensuring editorial independence and quality. The journal publishes work spanning heterogeneous catalysis, homogeneous catalysis, and biocatalysis, covering areas such as catalytic synthesis, mechanisms, characterization, computational studies, nanoparticle catalysis, electrocatalysis, photocatalysis, environmental catalysis, asymmetric catalysis, and various forms of organocatalysis.