Biological validation of peak-width of skeletonized mean diffusivity as a VCID biomarker: The MarkVCID Consortium

IF 13 1区医学 Q1 CLINICAL NEUROLOGY

Alzheimer's & Dementia Pub Date : 2024-11-21 DOI:10.1002/alz.14345

Alison M. Luckey, Saptaparni Ghosh, Chen-Pin Wang, Alexa Beiser, Rebecca Bernal, Zhiguang Li, Djass Mbangdadji, Elyas Fadaee, Haykel Snoussi, Angel Gabriel Velarde Dediós, Hector A. Trevino, Monica Goss, Laura J. Hillmer, Christopher E. Bauer, Adam M. Staffaroni, Lara Stables, Marilyn Albert, Jayandra J. Himali, Thomas H. Mosley, Lars Forsberg, Vilmundur Guðnason, Baljeet Singh, Herpreet Singh, Kristin Schwab, Joel H. Kramer, Gary A. Rosenberg, Karl G. Helmer, Steven M. Greenberg, Mohamad Habes, Danny J. J. Wang, Brian T. Gold, Hanzhang Lu, Arvind Caprihan, Myriam Fornage, Lenore J. Launer, Konstantinos Arfanakis, Sudha Seshadri, Charles DeCarli, Pauline Maillard, Claudia L. Satizabal

引用次数: 0

Abstract

Peak-width of skeletonized mean diffusivity (PSMD), a neuroimaging marker of cerebral small vessel disease (SVD), has shown excellent instrumental properties. Here, we extend our work to perform a biological validation of PSMD.

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将骨架化平均扩散率峰值宽度作为 VCID 生物标记物的生物学验证MarkVCID 联合会

骨架化平均扩散率峰值宽度（PSMD）是脑小血管疾病（SVD）的神经影像标记物，具有出色的仪器特性。在此，我们扩展了我们的工作，对 PSMD 进行了生物学验证。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Alzheimer's & Dementia 医学-临床神经学

CiteScore

14.50

自引率

5.00%

发文量

299

审稿时长

3 months

期刊介绍： Alzheimer's & Dementia is a peer-reviewed journal that aims to bridge knowledge gaps in dementia research by covering the entire spectrum, from basic science to clinical trials to social and behavioral investigations. It provides a platform for rapid communication of new findings and ideas, optimal translation of research into practical applications, increasing knowledge across diverse disciplines for early detection, diagnosis, and intervention, and identifying promising new research directions. In July 2008, Alzheimer's & Dementia was accepted for indexing by MEDLINE, recognizing its scientific merit and contribution to Alzheimer's research.