Thyroid cancer metastasis to the pituitary fossa: A clinical analysis and literature review.

IF 0.8 4区医学 Q4 CLINICAL NEUROLOGY

Clinical Neuropathology Pub Date : 2024-11-20 DOI:10.5414/NP301649

Damjan Veljanoski, Agbolahan Sofela, Abdel-Rahman Abdel-Fattah, Aditya Shivane, Samiul Muquit

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引用次数: 0

Abstract

Background: A 71-year-old man presented with a history of headaches, blurred vision, diplopia, and right-sided ptosis. Magnetic resonance imaging (MRI) of the head revealed a 2.5 cm pituitary fossa lesion distorting the optic chiasm, with cavernous sinus invasion and frontal, temporal, and parieto-occipital lesions. Computed tomography (CT) found a retrosternal thyroid goiter. Biopsy of the occipital lobe lesion revealed metastatic papillary adenocarcinoma. Ultrasound-guided fine needle aspiration of the goiter and abnormal lymph nodes revealed Thy5. The patient underwent endoscopic transsphenoidal resection of the pituitary tumor, confirming papillary carcinoma of the thyroid. We sought to understand the clinico-radiological and histopathological features, treatment strategies, and outcomes of patients with thyroid cancer metastasis to the pituitary fossa.

Materials and methods: A date- and language-unrestricted literature search was performed across the MEDLINE, Embase, and Scopus databases using keywords relating to metastasis, the pituitary and thyroid glands, and the brain. Citations reporting patients with thyroid metastasis to the pituitary fossa were included. A proforma was used to extract and store data from the included citations.

Results: After deduplication, 2,833 citations were screened for eligibility, and 49 citations were included in the analysis.

Conclusion: We present a rare case illustration and comprehensive literature review of patients with thyroid cancer metastasis to the pituitary fossa.

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甲状腺癌转移至垂体窝：临床分析和文献综述。

背景：一名 71 岁的男子因头痛、视力模糊、复视和右侧眼睑下垂前来就诊。头部磁共振成像（MRI）显示垂体窝有 2.5 厘米的病变，扭曲了视交叉，并伴有海绵窦侵犯、额叶、颞叶和顶枕叶病变。计算机断层扫描（CT）发现胸骨后甲状腺肿。枕叶病变活检显示为转移性乳头状腺癌。超声引导下对甲状腺肿和异常淋巴结进行细针穿刺发现了Thy5。患者接受了内镜下经蝶垂体瘤切除术，确诊为甲状腺乳头状腺癌。我们试图了解甲状腺癌转移至垂体窝患者的临床放射学和组织病理学特征、治疗策略和预后：在MEDLINE、Embase和Scopus数据库中使用与转移、垂体和甲状腺以及大脑相关的关键词进行了日期和语言不限的文献检索。报告甲状腺转移至垂体窝患者的文献也包括在内。结果：结果：经过去重后，共筛选出 2,833 篇符合条件的引文，其中 49 篇被纳入分析：我们对甲状腺癌转移至垂体窝的患者进行了罕见的病例说明和全面的文献综述。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical Neuropathology 医学-病理学

CiteScore

1.60

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： Clinical Neuropathology appears bi-monthly and publishes reviews and editorials, original papers, short communications and reports on recent advances in the entire field of clinical neuropathology. Papers on experimental neuropathologic subjects are accepted if they bear a close relationship to human diseases. Correspondence (letters to the editors) and current information including book announcements will also be published.