Daniele Cardaropoli, Lorenzo Tamagnone, Luigi Laino, Lorena Gaveglio
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引用次数: 0
Abstract
Background: Soft tissue healing is of paramount importance when guided bone regeneration techniques are used, as early exposure of the membrane could affect the results.
Methods: In this randomized clinical trial, enrolling 20 patients, a gel rich in hyaluronic acid and amino acids was used to promote wound healing after a ridge augmentation procedure. The Early Wound Healing Index - EHS was used to assess soft tissue healing by primary intention following surgery at 1, 3, 7 and 14 days.
Results: Results showed faster tissue healing when hyaluronic acid mixed with amino acids was used, and also a lower perception of pain by patients measured with a VAS scale.
Conclusions: These data suggest the creation of larger research studies that can support the use of biologics for early soft tissue healing.
背景：在使用引导骨再生技术时，软组织愈合至关重要，因为早期的骨膜暴露可能会影响效果：在这项随机临床试验中，20 名患者使用了一种富含透明质酸和氨基酸的凝胶来促进隆鼻术后的伤口愈合。采用早期伤口愈合指数（EHS）评估术后1、3、7和14天的软组织愈合情况：结果表明，使用混合了氨基酸的透明质酸时，组织愈合速度更快，使用 VAS 量表测量的患者疼痛感也更低：这些数据建议开展更大规模的研究，以支持生物制剂用于早期软组织愈合。
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