Worldwide Research Trends and Regional Differences in the Development of Precision Medicine Under Data-Driven Approach: A Bibliometric Analysis.

IF 2.7 3区 医学 Q2 HEALTH CARE SCIENCES & SERVICES
Journal of Multidisciplinary Healthcare Pub Date : 2024-11-15 eCollection Date: 2024-01-01 DOI:10.2147/JMDH.S482543
Heyuan Niu, Kai Yu Li, Tao Yu, Maorun Zhang, Zhe Ji, Ping Yu, Xianfu Yi, Gang Liu
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引用次数: 0

Abstract

Background: Precision medicine is an innovative approach that integrates genomics, clinical informatics, and proteomics to address both genetic and environmental factors in disease prevention and treatment. This bibliometric study analyzes research trends, collaboration patterns, and the unique characteristics of precision medicine across countries to inform future research directions.

Methods: A comprehensive search was conducted in the Web of Science Core Collection (1999-2022) database to identify publications related to precision medicine. The analysis of publication patterns, collaborations, institutions, authors, and research hotspots was performed utilizing Microsoft PowerPoint 2019 in conjunction with the Bibliometrix package in R.

Results: A total of 30,777 publications on precision medicine were identified. The United States and the United Kingdom were recognized as the primary contributors, while European countries exhibited substantial collaborative efforts. Harvard University and the University of California System have played pivotal roles in advancing the field. The keywords analysis showed that in the early 2000s, "gene expression" and "personalized outcomes" were key themes. Since 2015, there's been a significant shift towards advanced technologies like artificial intelligence, machine learning, liquid biopsy, highlighting their growing importance in precision medicine. Research topics across various countries exhibit certain global similarities. However, different nations exhibit distinct thematic research focuses. China emphasizes "Informatics", "Hepatocellular Carcinoma", "Photothermal Therapy", and "Lung Adenocarcinoma", while the United States prioritizes "Informatics", "Treatment Rules", and "Consortium Guidelines". Germany and France share similar interests in particular research domains.

Conclusion: Precision medicine is rapidly globalizing, with significant contributions from multiple countries and emerging technologies acting as catalysts for further development. Greater international cooperation is essential to elevate the quality and impact of research. These advancements hold great potential for transforming personalized healthcare by integrating cutting-edge scientific disciplines.

数据驱动方法下精准医学发展的全球研究趋势和地区差异:文献计量分析。
背景:精准医学是一种创新方法,它整合了基因组学、临床信息学和蛋白质组学,以解决疾病预防和治疗中的遗传和环境因素问题。这项文献计量学研究分析了各国的研究趋势、合作模式以及精准医学的独特性,为未来的研究方向提供了参考:方法:在科学网核心数据库(1999-2022 年)中进行了全面搜索,以确定与精准医学相关的出版物。利用 Microsoft PowerPoint 2019 和 R 中的 Bibliometrix 软件包对出版物模式、合作、机构、作者和研究热点进行了分析:结果:共发现了 30777 篇有关精准医学的出版物。美国和英国被认为是主要的贡献者,而欧洲国家则展示了大量的合作成果。哈佛大学和加州大学系统在推动这一领域的发展方面发挥了关键作用。关键词分析显示,本世纪初,"基因表达 "和 "个性化结果 "是关键主题。自 2015 年以来,人工智能、机器学习、液体活检等先进技术出现了显著转变,凸显了它们在精准医疗中日益增长的重要性。各国的研究主题在全球范围内呈现出一定的相似性。然而,不同国家的专题研究重点各不相同。中国强调 "信息学"、"肝细胞癌"、"光热疗法 "和 "肺腺癌",而美国则优先考虑 "信息学"、"治疗规则 "和 "联盟指南"。德国和法国在特定研究领域有着相似的兴趣:结论:精准医学正在迅速全球化,来自多个国家的重要贡献和新兴技术成为进一步发展的催化剂。加强国际合作对于提高研究质量和影响力至关重要。通过整合尖端科学学科,这些进步为改变个性化医疗保健带来了巨大潜力。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Journal of Multidisciplinary Healthcare
Journal of Multidisciplinary Healthcare Nursing-General Nursing
CiteScore
4.60
自引率
3.00%
发文量
287
审稿时长
16 weeks
期刊介绍: The Journal of Multidisciplinary Healthcare (JMDH) aims to represent and publish research in healthcare areas delivered by practitioners of different disciplines. This includes studies and reviews conducted by multidisciplinary teams as well as research which evaluates or reports the results or conduct of such teams or healthcare processes in general. The journal covers a very wide range of areas and we welcome submissions from practitioners at all levels and from all over the world. Good healthcare is not bounded by person, place or time and the journal aims to reflect this. The JMDH is published as an open-access journal to allow this wide range of practical, patient relevant research to be immediately available to practitioners who can access and use it immediately upon publication.
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