Peptides in the Treatment of Gastric Ulcer.

IF 0.9 4区医学 Q4 MEDICINE, RESEARCH & EXPERIMENTAL

Bulletin of Experimental Biology and Medicine Pub Date : 2024-11-20 DOI:10.1007/s10517-024-06272-z

A S Kalnitsky, A Yu Zharikov

引用次数: 0

Abstract

A promising area in the search for effective and safe methods of pharmacotherapy for gastric ulcers is the study of bioactive substances of natural origin and derivatives synthesized on the basis of these substances. The review presents modern information on various peptide-based substances that are pharmacologically active against gastric ulcer, including analogues of natural neuropeptides, synthetic substances with a specific amino acid sequence, as well as drugs derived from biological peptide complexes. Based on the results of the analysis, we have assessed the prospects of this pharmacological approach and outlined the areas for further research.

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多肽治疗胃溃疡。

在寻找有效、安全的胃溃疡药物治疗方法的过程中，研究天然来源的生物活性物质和在这些物质基础上合成的衍生物是一个很有前景的领域。这篇综述介绍了对胃溃疡具有药理活性的各种肽类物质的现代信息，包括天然神经肽的类似物、具有特定氨基酸序列的合成物质以及从生物肽复合物中提取的药物。根据分析结果，我们评估了这种药理学方法的前景，并概述了进一步研究的领域。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Bulletin of Experimental Biology and Medicine 医学-医学：研究与实验

CiteScore

1.50

自引率

14.30%

发文量

265

审稿时长

2 months

期刊介绍： Bulletin of Experimental Biology and Medicine presents original peer reviewed research papers and brief reports on priority new research results in physiology, biochemistry, biophysics, pharmacology, immunology, microbiology, genetics, oncology, etc. Novel trends in science are covered in new sections of the journal - Biogerontology and Human Ecology - that first appeared in 2005. World scientific interest in stem cells prompted inclusion into Bulletin of Experimental Biology and Medicine a quarterly scientific journal Cell Technologies in Biology and Medicine (a new Russian Academy of Medical Sciences publication since 2005). It publishes only original papers from the leading research institutions on molecular biology of stem and progenitor cells, stem cell as the basis of gene therapy, molecular language of cell-to-cell communication, cytokines, chemokines, growth and other factors, pilot projects on clinical use of stem and progenitor cells. The Russian Volume Year is published in English from April.