Microviridae bacteriophages in the gut microbiome and food addiction in humans

IF 18.9 1区医学 Q1 ENDOCRINOLOGY & METABOLISM

Nature metabolism Pub Date : 2024-11-20 DOI:10.1038/s42255-024-01158-w

引用次数: 0

Abstract

Despite their abundance and despite being the most numerous biological entities on Earth, viruses remain one of the least understood components of the human microbiome. In our study, we show how Microviridae bacteriophages in the gut microbiome are associated with food addiction through changes in tryptophan, serotonin and dopamine metabolism.

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人类肠道微生物群中的微病毒科噬菌体与食物成瘾

病毒是地球上数量最多的生物实体，尽管数量巨大，但它们仍然是人类微生物组中最不为人知的组成部分之一。在我们的研究中，我们展示了肠道微生物组中的微小病毒科噬菌体如何通过改变色氨酸、血清素和多巴胺的代谢与食物成瘾有关。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Nature metabolism ENDOCRINOLOGY & METABOLISM-

CiteScore

27.50

自引率

2.40%

发文量

170

期刊介绍： Nature Metabolism is a peer-reviewed scientific journal that covers a broad range of topics in metabolism research. It aims to advance the understanding of metabolic and homeostatic processes at a cellular and physiological level. The journal publishes research from various fields, including fundamental cell biology, basic biomedical and translational research, and integrative physiology. It focuses on how cellular metabolism affects cellular function, the physiology and homeostasis of organs and tissues, and the regulation of organismal energy homeostasis. It also investigates the molecular pathophysiology of metabolic diseases such as diabetes and obesity, as well as their treatment. Nature Metabolism follows the standards of other Nature-branded journals, with a dedicated team of professional editors, rigorous peer-review process, high standards of copy-editing and production, swift publication, and editorial independence. The journal has a high impact factor, has a certain influence in the international area, and is deeply concerned and cited by the majority of scholars.