Synthesis of Betulin and Allobetulin Derivatives Containing Heterylthioacetoxyl Groups

IF 0.9 4区化学 Q4 CHEMISTRY, MULTIDISCIPLINARY

Russian Journal of General Chemistry Pub Date : 2024-11-19 DOI:10.1134/S1070363224100074

Yu. G. Trishin, E. D. Vakhrusheva, N. A. Anisimova, O. Y. Derkacheva, R. I. Baichurin, I. Kh. Rizvanov

引用次数: 0

Abstract

Previously unknown betulin and allobetulin derivatives, which are of interest as potential biologically active substances, were synthesized by replacing chlorine in 3,28-bis(chloroacetoxy)betulin and 3-chloroacetoxyallobetulin with pharmacophoric cycloheteryl sulfide groups.

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含异巯基乙酰氧基的桦木醇和阿洛勃林衍生物的合成

通过将 3,28-双（氯乙酰氧基）白桦脂素和 3-氯乙酰氧基白桦脂素中的氯替换为具有药效的环庚基硫醚基团，合成了以前未知的白桦脂素和白桦脂素衍生物，这些衍生物具有潜在的生物活性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Russian Journal of General Chemistry 化学-化学综合

CiteScore

1.40

自引率

22.20%

发文量

252

审稿时长

2-4 weeks

期刊介绍： Russian Journal of General Chemistry is a journal that covers many problems that are of general interest to the whole community of chemists. The journal is the successor to Russia’s first chemical journal, Zhurnal Russkogo Khimicheskogo Obshchestva (Journal of the Russian Chemical Society ) founded in 1869 to cover all aspects of chemistry. Now the journal is focused on the interdisciplinary areas of chemistry (organometallics, organometalloids, organoinorganic complexes, mechanochemistry, nanochemistry, etc.), new achievements and long-term results in the field. The journal publishes reviews, current scientific papers, letters to the editor, and discussion papers.