Cobalt-Catalyzed Regioselective C8-H Sulfoxamination of 1-Naphthylamine Derivatives with NH-Sulfoximines.

IF 3.3 2区化学 Q1 CHEMISTRY, ORGANIC

Journal of Organic Chemistry Pub Date : 2024-12-20 Epub Date: 2024-11-18 DOI:10.1021/acs.joc.4c02318

Nileshkumar B Rathod, Raj N Patel, Sachinkumar D Patel, Dharmik M Patel, Mahesh A Sonawane, Dinesh Gopichand Thakur, Subhash Chandra Ghosh

引用次数: 0

Abstract

A simple cobalt-catalyzed, picolinamide-directed C8-H sulfoxamination of 1-naphthalamides with NH-sulfoximines has been developed. This cross-dehydrogenative C-H/N-H coupling reaction offers a facile route to N-arylated sulfoximines, exhibiting high yields, a broad substrate scope, and excellent functional group tolerance and scalability.

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钴催化的 1-萘胺衍生物与 NH-亚磺酰亚胺的 Regioselective C8-H Sulfoxamination。

我们开发了一种简单的钴催化、皮啶胺指导的 1-萘甲酰胺与 NH-亚磺酰亚胺的 C8-H 磺化反应。这种交叉脱氢 C-H/N-H 偶联反应为 N-芳基化的亚磺酰亚胺提供了一条简便的途径，具有产率高、底物范围广、官能团耐受性好和可扩展性强等特点。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Organic Chemistry 化学-有机化学

CiteScore

6.20

自引率

11.10%

发文量

1467

审稿时长

2 months

期刊介绍： Journal of Organic Chemistry welcomes original contributions of fundamental research in all branches of the theory and practice of organic chemistry. In selecting manuscripts for publication, the editors place emphasis on the quality and novelty of the work, as well as the breadth of interest to the organic chemistry community.