Ayurveda interventions for non-specific chronic low back pain— protocol for a systematic review and network meta-analysis

IF 1.9 4区医学 Q3 INTEGRATIVE & COMPLEMENTARY MEDICINE

European Journal of Integrative Medicine Pub Date : 2024-10-19 DOI:10.1016/j.eujim.2024.102413

Ritu Kumari, Mandip Goyal, Kalpesh Panara

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引用次数: 0

Abstract

Introduction

Low back pain (570 million prevalent cases worldwide) is the main contributor to the overall burden of musculoskeletal conditions. The most common form of low back pain is non-specific low back pain (NSCLBP) (almost 90 %). There are no treatments that completely cure chronic low back pain. Ayurveda is one of the traditional systems of Indian medicine commonly practiced in Southeast Asian countries. Even though Ayurveda interventions (oral medication or procedure-based treatment or combined therapy) are practiced widely for this condition, there is ambiguity about the hierarchy of treatment. The present review has been planned to compare all the available Ayurveda treatment modalities for NSCLBP in terms of efficacy, and safety, in all the age groups of patients.

Methods

This review will be written in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) and the PRISMA extension for network meta-analyses. Electronic searches will be carried out in PubMed, Scopus, TRIP, Website of Indexing of Indian Medical Journals, the Cochrane Register for Controlled Trials, The Clinical Trials Registry- India, AYUSH research portal, and Digital Helpline for Ayurveda Research Articles, and other pre-print repositories since its inception till 31st March 2024. Randomized controlled trials, randomized cross-over studies, cluster-randomized studies, and nonrandomized studies of interventions (prospective cohort studies, non-randomized clinical trials) will be included. The risk of bias will be assessed with ROB-2, ROBINS-I, and other revised risk of bias tools for cross-over studies and cluster randomised studies recommended by the Cochrane collaboration. To evaluate the credibility of the findings, the Grading of Recommendations Assessment, Development, and Evaluation method for network meta-analysis will be implemented. A narrative approach to synthesize and report qualitative and quantitative data will be used, and where feasible, we will conduct network meta-analyses using STATA software.

Conclusions

This protocol defines a plan of the study that would facilitate the process of recommending treatment for NSCLBP, by providing a treatment hierarchy of Ayurvedic treatment to the policymakers and stakeholders.

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阿育吠陀对非特异性慢性腰背痛的干预--系统综述和网络荟萃分析方案

导言腰背痛（全球有 5.7 亿发病病例）是造成肌肉骨骼疾病总体负担的主要因素。最常见的腰背痛是非特异性腰背痛（NSCLBP）（近 90%）。目前还没有完全治愈慢性腰背痛的疗法。阿育吠陀是印度的传统医学体系之一，在东南亚国家很普遍。尽管阿育吠陀疗法（口服药物、程序性治疗或综合疗法）被广泛用于治疗这种病症，但在治疗的层次上却存在模糊不清的地方。本综述计划比较所有可用的阿育吠陀治疗 NSCLBP 的方法对所有年龄组患者的疗效和安全性。方法本综述将根据系统综述和荟萃分析首选报告项目（PRISMA）和网络荟萃分析 PRISMA 扩展项目撰写。电子检索将在 PubMed、Scopus、TRIP、印度医学期刊索引网站、Cochrane 对照试验注册中心、印度临床试验注册中心、AYUSH 研究门户网站、阿育吠陀研究文章数字帮助热线和其他预印本资料库中进行，检索时间从开始至 2024 年 3 月 31 日。将纳入随机对照试验、随机交叉研究、群组随机研究和非随机干预研究（前瞻性队列研究、非随机临床试验）。将使用 ROB-2、ROBINS-I 以及 Cochrane 协作组织推荐的用于交叉研究和群组随机研究的其他修订版偏倚风险工具来评估偏倚风险。为了评估研究结果的可信度，将采用网络荟萃分析的建议分级评估、发展和评价方法。我们将采用叙事方法来综合和报告定性与定量数据，在可行的情况下，我们将使用 STATA 软件进行网络荟萃分析。结论本方案确定了一项研究计划，通过向政策制定者和利益相关者提供阿育吠陀疗法的治疗层次结构，促进推荐治疗 NSCLBP 的进程。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

European Journal of Integrative Medicine INTEGRATIVE & COMPLEMENTARY MEDICINE-

CiteScore

4.70

自引率

4.00%

发文量

102

审稿时长

33 days

期刊介绍： The European Journal of Integrative Medicine (EuJIM) considers manuscripts from a wide range of complementary and integrative health care disciplines, with a particular focus on whole systems approaches, public health, self management and traditional medical systems. The journal strives to connect conventional medicine and evidence based complementary medicine. We encourage submissions reporting research with relevance for integrative clinical practice and interprofessional education. EuJIM aims to be of interest to both conventional and integrative audiences, including healthcare practitioners, researchers, health care organisations, educationalists, and all those who seek objective and critical information on integrative medicine. To achieve this aim EuJIM provides an innovative international and interdisciplinary platform linking researchers and clinicians. The journal focuses primarily on original research articles including systematic reviews, randomized controlled trials, other clinical studies, qualitative, observational and epidemiological studies. In addition we welcome short reviews, opinion articles and contributions relating to health services and policy, health economics and psychology.