Short and long-term clinical results of a minimally invasive syringe adapter for catheter free instillation of intravesical treatments

Abstract

Introduction:

Intravesical treatment is currently dependent on catheterization which can cause urethral discomfort and risk of urinary tract infections in selected patient groups such as interstitial cystitis/bladder pain syndrome (IC/BPS), overactive bladder syndrome (OAB) and recurrent urinary tract infections (rUTI). This study describes real-life clinical experience of a minimally invasive syringe adapter (Ialuadapter®) for catheter-free instillation of intravesical treatment.

Methods:

A retrospective study from a single center was performed. Quantitative and qualitative data was obtained on the use of the syringe adapter (Ialuadapter®) in 61 patients with IC/BPS (n=48), rUTI (n=6) and mixed /other diagnoses (including OAB; n= 7) who were receiving intravesical therapy. The evaluation period was 6 months during 2018–2019. Reasons for trying the syringe adapter, reasons for continuing with it and occurrence of UTIs before and during the evaluation period were recorded. In addition, 3 year follow-up data were obtained to assess long-term usage of the syringe adapter.

Results:

Mean follow-up was 4 months. The use of the syringe adapter was successful in 75% and a positive experience in 74% with the latter continuing to use the syringe adapter. Long-term (>3 yrs) adherence of 40% was observed. The patients reported less pain (41%) while 23% reported that it was easier to use compared to conventional catheters. Only 6 UTIs were observed in the follow-up period.

Discussion and conclusions:

This retrospective study shows that the Ialuadapter® is a good, safe alternative to conventional catheterization for intravesical treatment.