A recent update on pallavicinia diterpenoids: Isolation, biogenetic pathway and total synthesis

Abstract

Pallavicinia diterpenoids are isolated from the genus Pallavicinia of liverworts. Herein, the isolation, biogenetic pathway and total synthesis of pallavicinia diterpenoids with four distinct and complex skeletons were discribed. In this review, all successful total syntheses of 16 pallavicinia diterpenoids were introduced respectively in detail. These outstanding synthetic work will provide more inspiration and pave the stage for ingenious and efficient synthesis of newly discovered pallavicinia diterpenoids as well as other complex natural products, further promoting comprehensive biological evaluation.