{"title":"Increased attention to women with drug-induced liver injury: Risk factors and early intervention","authors":"Xiaoru Sun , Xinrong Zhang , Muyun Liu","doi":"10.1016/j.iliver.2024.100125","DOIUrl":null,"url":null,"abstract":"<div><div>A recent study by Xiong Yu-Ting and colleagues has unveiled the clinical characteristics and risk factors of acute drug-induced liver injury (DILI). Upon reading the article, we found that there are some differences between female and male patients with DILI in terms of clinical and pathological features, especially in the number of patients, the degree of liver inflammation, and the risk of autoimmune liver disease. Therefore, it is necessary to pay attention to female patients with DILI and their outcomes, and to intervene appropriately in advance. This article analyzes the reasons for the differences between female and male patients with DILI and makes recommendations for patient prognosis.</div></div>","PeriodicalId":100657,"journal":{"name":"iLIVER","volume":"3 4","pages":"Article 100125"},"PeriodicalIF":0.0000,"publicationDate":"2024-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"iLIVER","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2772947824000501","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
A recent study by Xiong Yu-Ting and colleagues has unveiled the clinical characteristics and risk factors of acute drug-induced liver injury (DILI). Upon reading the article, we found that there are some differences between female and male patients with DILI in terms of clinical and pathological features, especially in the number of patients, the degree of liver inflammation, and the risk of autoimmune liver disease. Therefore, it is necessary to pay attention to female patients with DILI and their outcomes, and to intervene appropriately in advance. This article analyzes the reasons for the differences between female and male patients with DILI and makes recommendations for patient prognosis.
熊玉婷及其同事最近的一项研究揭示了急性药物性肝损伤(DILI)的临床特征和风险因素。通过阅读文章,我们发现女性和男性 DILI 患者在临床和病理特征方面存在一定差异,尤其是在患者人数、肝脏炎症程度和自身免疫性肝病风险方面。因此,有必要关注女性 DILI 患者及其结局,并提前进行适当干预。本文分析了DILI女性患者与男性患者存在差异的原因,并对患者的预后提出了建议。