Ping Xue, Lei Guo, E Dang, Wenjie Dou, Xianhui Zeng, Xing Fan, Qing Yang
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引用次数: 0
Abstract
Background: Androgenetic alopecia (AGA) is the most prevalent type of hair loss. Traditionally, treatment for AGA has primarily involved the topical application of minoxidil in conjunction with oral finasteride or spironolactone. Recently, platelet-rich plasma (PRP) has emerged as a significant focus of research in hair loss treatment. However, many studies on PRP-assisted hair transplantation have encountered various limitations.
Objective: This study aims to conduct a prospective, comparative clinical investigation to evaluate the therapeutic effects of combining PRP with minoxidil and finasteride/spironolactone as adjuncts to hair transplantation.
Method: From August 2019 to December 2022, we enrolled 30 patients with AGA in the study, randomly assigning them to an experimental group and a control group. The experimental group received drug therapy alongside hair transplantation and underwent PRP injections, whereas the control group received only drug therapy to assist with hair transplantation.
Results: Prior to surgery, no significant differences in baseline data were observed between the two groups. Following treatment, the experimental group demonstrated significantly improved follicle survival rates, follicle growth rates, and hair strength compared with the control group.
Conclusion: This prospective, comparative clinical study demonstrated that the application of PRP in conjunction with pharmacological support during FUE treatment for AGA resulted in improved follicle survival rates, hair growth rates, and hair strength.
背景：雄激素性脱发（AGA）是最常见的脱发类型。传统上，治疗 AGA 的方法主要是局部使用米诺地尔，同时口服非那雄胺或螺内酯。最近，富血小板血浆（PRP）成为脱发治疗研究的重点。然而，许多关于 PRP 辅助植发的研究都遇到了各种限制：本研究旨在开展一项前瞻性、对比性临床调查，评估 PRP 与米诺地尔、非那雄胺/螺内酯联合作为植发手术辅助药物的治疗效果：2019年8月至2022年12月，我们招募了30名AGA患者参与研究，将他们随机分配到实验组和对照组。实验组在接受植发手术的同时接受药物治疗，并进行PRP注射，而对照组仅接受药物治疗辅助植发手术：结果：手术前，两组的基线数据无明显差异。治疗后，与对照组相比，实验组的毛囊存活率、毛囊生长率和头发强度都有明显提高：这项前瞻性、对比性临床研究表明，在 FUE 治疗 AGA 的过程中，应用 PRP 并结合药物支持可提高毛囊存活率、毛发生长率和毛发强度。
期刊介绍：
The Journal of Cosmetic Dermatology publishes high quality, peer-reviewed articles on all aspects of cosmetic dermatology with the aim to foster the highest standards of patient care in cosmetic dermatology. Published quarterly, the Journal of Cosmetic Dermatology facilitates continuing professional development and provides a forum for the exchange of scientific research and innovative techniques.
The scope of coverage includes, but will not be limited to: healthy skin; skin maintenance; ageing skin; photodamage and photoprotection; rejuvenation; biochemistry, endocrinology and neuroimmunology of healthy skin; imaging; skin measurement; quality of life; skin types; sensitive skin; rosacea and acne; sebum; sweat; fat; phlebology; hair conservation, restoration and removal; nails and nail surgery; pigment; psychological and medicolegal issues; retinoids; cosmetic chemistry; dermopharmacy; cosmeceuticals; toiletries; striae; cellulite; cosmetic dermatological surgery; blepharoplasty; liposuction; surgical complications; botulinum; fillers, peels and dermabrasion; local and tumescent anaesthesia; electrosurgery; lasers, including laser physics, laser research and safety, vascular lasers, pigment lasers, hair removal lasers, tattoo removal lasers, resurfacing lasers, dermal remodelling lasers and laser complications.
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