Treatment of Mid-Face Aging with Calcium Hydroxylapatite: Focus on Retaining Ligament Support.

IF 1.9 4区 医学 Q3 DERMATOLOGY
Clinical, Cosmetic and Investigational Dermatology Pub Date : 2024-11-11 eCollection Date: 2024-01-01 DOI:10.2147/CCID.S468447
Mauricio Sato, Mariana Muniz, Luis Ricardo Coelho Ferreira
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引用次数: 0

Abstract

The mid-face has been rendered as the cornerstone of facial aesthetic improvement, since treating the mid-face has also beneficial effects on neighboring esthetic units and therefore should be one of the first areas to be assessed. Retaining ligaments (RL) bind soft tissue layers of the face to the underlying facial skeleton. It remains controversial whether RL suffers laxity with aging or if changes in 42 bone and other structures where ligaments are inserted lead to altered mechanical function of the latter. Enhancement of the supportive effect of the ligaments could help restore the soft tissues to their original anatomical positions and achieve a lifting effect. While injectable hyaluronic acid implants have been used to improve ligament support, calcium hydroxylapatite has one of the highest viscoelasticities when compared with other dermal fillers and can induce collagen synthesis, which could provide long-term laxity correction. In this preliminary report of a case series, our goal was to describe the use of calcium hydroxylapatite in different dilutions and combinations for different aging profiles to treat the midface as an alternative for hyaluronic acid injections and to describe the ultrasonographic behavior in the long run.

用羟基磷灰石钙治疗中面部老化:注重保留韧带支撑。
中面部被视为面部美学改善的基石,因为对中面部的治疗也会对邻近的美学单元产生有益的影响,因此中面部应该是最先被评估的部位之一。保持韧带(RL)将面部软组织层与下层面部骨骼结合在一起。韧带是否会随着年龄的增长而松弛,或者韧带所在的 42 块骨骼和其他结构的变化是否会导致韧带的机械功能发生改变,目前仍存在争议。增强韧带的支撑作用有助于将软组织恢复到原来的解剖位置,达到提升效果。虽然透明质酸注射植入物已被用于改善韧带支撑效果,但与其他皮肤填充物相比,羟基磷灰石钙具有最高的粘弹性,可诱导胶原蛋白合成,从而实现长期松弛矫正。在这份病例系列的初步报告中,我们的目标是描述不同稀释度和不同组合的羟基磷灰石钙在治疗中面部老化方面的应用,以替代透明质酸注射,并描述超声波的长期表现。
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来源期刊
CiteScore
2.80
自引率
4.30%
发文量
353
审稿时长
16 weeks
期刊介绍: Clinical, Cosmetic and Investigational Dermatology is an international, peer-reviewed, open access journal that focuses on the latest clinical and experimental research in all aspects of skin disease and cosmetic interventions. Normal and pathological processes in skin development and aging, their modification and treatment, as well as basic research into histology of dermal and dermal structures that provide clinical insights and potential treatment options are key topics for the journal. Patient satisfaction, preference, quality of life, compliance, persistence and their role in developing new management options to optimize outcomes for target conditions constitute major areas of interest. The journal is characterized by the rapid reporting of clinical studies, reviews and original research in skin research and skin care. All areas of dermatology will be covered; contributions will be welcomed from all clinicians and basic science researchers globally.
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