Electrochemically Induced, Metal Free Synthesis of 2-substituted chroman-4-ones.

IF 2.5 4区化学 Q2 CHEMISTRY, MULTIDISCIPLINARY

ChemistryOpen Pub Date : 2024-11-16 DOI:10.1002/open.202400395

Mohsen Monirialamdari, Aleksandra Podlaska, Dominika Pomikło, Anna Albrecht

引用次数: 0

Abstract

Electrochemically induced, decarboxylative functionalization of chromone-3-carboxylic acids by N-hydroxyphthalimide esters as alkyl radical precursors was studied. Electrochemical protocol offers a sustainable and green approach, obviating the need for catalysts, relying on the direct reduction of NHPI esters using electric current. Developed protocol provides a straightforward route to the synthesis of diverse molecules with potential biological activity.

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电化学诱导的 2-取代色满-4-酮的无金属合成。

研究了以 N-羟基邻苯二甲酰亚胺酯为烷基自由基前体，通过电化学方法诱导色酮-3-羧酸的脱羧功能化。电化学方案提供了一种可持续的绿色方法，无需催化剂，依靠电流直接还原 NHPI 酯。所开发的方案为合成具有潜在生物活性的多种分子提供了一条直接的途径。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

ChemistryOpen CHEMISTRY, MULTIDISCIPLINARY-

CiteScore

4.80

自引率

4.30%

发文量

143

审稿时长

1 months

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