Topical Nanoliposomal Collagen Delivery for Targeted Fibril Formation by Electrical Stimulation (Adv. Healthcare Mater. 28/2024)

IF 10 2区医学 Q1 ENGINEERING, BIOMEDICAL

Advanced Healthcare Materials Pub Date : 2024-11-11 DOI:10.1002/adhm.202470180

Albertus Ivan Brilian, Sang Ho Lee, Agustina Setiawati, Chang Ho Kim, Soo Ryeon Ryu, Hyo-Jin Chong, Yejin Jo, Hayan Jeong, Bong-Gun Ju, Oh-Sun Kwon, Giyoong Tae, Kwanwoo Shin

引用次数: 0

Abstract

Collagen Delivery

The cover of the article 2400693 by Giyoong Tae, Kwanwoo Shin, and co-workers showcases a novel mechanism: collagen monomers within lipid nanoparticles are applied to the skin and synthesized into collagen fibers within the dermal layer, facilitated by external electrical stimulation. This process is visualized to demonstrate that without electrical stimulation, the liposomes transport the monomers to the skin at a low pH, with synthesis solely occurring in the dermis.

Abstract Image

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通过电刺激局部纳米脂质体胶原蛋白定向纤维形成（Adv.）

胶原蛋白递送Giyoong Tae、Kwanwoo Shin 及合作者撰写的 2400693 号文章的封面展示了一种新的机制：脂质纳米粒子中的胶原蛋白单体被涂抹到皮肤上，并在外部电刺激的促进下在真皮层合成胶原纤维。这一过程的可视化表明，在没有电刺激的情况下，脂质体在低 pH 值下将单体输送到皮肤，合成仅在真皮层进行。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Advanced Healthcare Materials 工程技术-生物材料

CiteScore

14.40

自引率

3.00%

发文量

600

审稿时长

1.8 months

期刊介绍： Advanced Healthcare Materials, a distinguished member of the esteemed Advanced portfolio, has been dedicated to disseminating cutting-edge research on materials, devices, and technologies for enhancing human well-being for over ten years. As a comprehensive journal, it encompasses a wide range of disciplines such as biomaterials, biointerfaces, nanomedicine and nanotechnology, tissue engineering, and regenerative medicine.