Incidence, clinical manifestations and characterization of Enterovirus in the last decade (2014-2023) in Asturias (Spain). Effect of the SARS-CoV-2 pandemic.

IF 3.7 3区医学 Q2 INFECTIOUS DISEASES

European Journal of Clinical Microbiology & Infectious Diseases Pub Date : 2024-11-15 DOI:10.1007/s10096-024-04970-0

Susana Rojo-Alba, José María González-Alba, Zulema Pérez Martínez, Cristina Ochoa Varela, Maria Agustina Alonso Álvarez, Pablo Rubianes Fernández, Mercedes Rodríguez Pérez, Estibaliz Garrido García, José Antonio Boga, Santiago Melón García, Marta Elena Álvarez-Argüelles

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引用次数: 0

Abstract

Enteroviruses (EVs) are a large group of genotypes that cause a variety of pathologies, some of them very serious. This study analyzed the last 10 years (2014-2023) of EVs diagnosis and classification. In 166,674 samples collected, EVs were found in 9,535 (5.7%) by rt-RT-PCR, and 332 (3.5%) were classified by Sanger methods. Symptoms were analyzed in 7623 cases. EVs were found in 5718/63,829 (8.9%) before, 1384/42,373 (3.3%) during and 2433/60,472 (4%) after the Covid pandemic (p < 0.0001), and in 7249/69,700 (10.4%) children under 6 years and in 2286/96,974 (2.35%) in oldest (p < 0.0001). The positive rate of EVs was high but decreased during the Covid period. In the youngest children EVs-A (associated with exantematohous disorders as well as respiratory manifestations and febrile syndromes) was most common, while EVs-B (frequent in neurological symptoms) was most common in children aged 6-15 years and EVs-D (associated to respiratory manifestations) in adults.

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西班牙阿斯图里亚斯近十年（2014-2023 年）肠道病毒的发病率、临床表现和特征。SARS-CoV-2 大流行的影响。

肠道病毒（EVs）是一大类基因型病毒，可导致多种病症，其中一些病症非常严重。本研究分析了过去 10 年（2014-2023 年）的肠道病毒诊断和分类情况。在收集的 166674 份样本中，通过 rt-RT-PCR，发现 9535 份样本（5.7%）存在 EVs，通过 Sanger 方法，对 332 份样本（3.5%）进行了分类。对 7623 个病例的症状进行了分析。在 Covid 大流行之前、期间和之后，分别在 5718/63829 例（8.9%）、1384/42373 例（3.3%）和 2433/60472 例（4%）病例中发现了 EVs（P＜0.05）。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

European Journal of Clinical Microbiology & Infectious Diseases 医学-传染病学

CiteScore

10.40

自引率

2.20%

发文量

138

审稿时长

1 months

期刊介绍： EJCMID is an interdisciplinary journal devoted to the publication of communications on infectious diseases of bacterial, viral and parasitic origin.