{"title":"FMRP gains mitochondrial fission control","authors":"Carissa L. Sirois, Soraya O. Sandoval, Xinyu Zhao","doi":"10.1038/s41556-024-01567-9","DOIUrl":null,"url":null,"abstract":"Mitochondrial fission and fusion are crucial for neurons. The RNA-binding protein FMRP regulates mitochondrial dynamics, including fusion and trafficking in neurons. A study now identifies a mechanism by which FMRP regulates mitochondrial fission.","PeriodicalId":18977,"journal":{"name":"Nature Cell Biology","volume":"26 12","pages":"2014-2015"},"PeriodicalIF":17.3000,"publicationDate":"2024-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nature Cell Biology","FirstCategoryId":"99","ListUrlMain":"https://www.nature.com/articles/s41556-024-01567-9","RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CELL BIOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Mitochondrial fission and fusion are crucial for neurons. The RNA-binding protein FMRP regulates mitochondrial dynamics, including fusion and trafficking in neurons. A study now identifies a mechanism by which FMRP regulates mitochondrial fission.
期刊介绍:
Nature Cell Biology, a prestigious journal, upholds a commitment to publishing papers of the highest quality across all areas of cell biology, with a particular focus on elucidating mechanisms underlying fundamental cell biological processes. The journal's broad scope encompasses various areas of interest, including but not limited to:
-Autophagy
-Cancer biology
-Cell adhesion and migration
-Cell cycle and growth
-Cell death
-Chromatin and epigenetics
-Cytoskeletal dynamics
-Developmental biology
-DNA replication and repair
-Mechanisms of human disease
-Mechanobiology
-Membrane traffic and dynamics
-Metabolism
-Nuclear organization and dynamics
-Organelle biology
-Proteolysis and quality control
-RNA biology
-Signal transduction
-Stem cell biology