Setting morphogen gradients

IF 26.8 1区医学 Q1 ENGINEERING, BIOMEDICAL

Nature Biomedical Engineering Pub Date : 2024-11-15 DOI:10.1038/s41551-024-01295-3

Valeria Caprettini

引用次数: 0

Abstract

DNA microbeads loaded with an agonist for Wnt and injected into retinal organoids allow for the spatiotemporal control of gradients of the morphogen to better direct organoid development and maturation.

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设置形态发生梯度

将装有 Wnt 激动剂的 DNA 微珠注射到视网膜器官组织中，可对形态发生器的梯度进行时空控制，从而更好地指导器官组织的发育和成熟。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Nature Biomedical Engineering Medicine-Medicine (miscellaneous)

CiteScore

45.30

自引率

1.10%

发文量

138

期刊介绍： Nature Biomedical Engineering is an online-only monthly journal that was launched in January 2017. It aims to publish original research, reviews, and commentary focusing on applied biomedicine and health technology. The journal targets a diverse audience, including life scientists who are involved in developing experimental or computational systems and methods to enhance our understanding of human physiology. It also covers biomedical researchers and engineers who are engaged in designing or optimizing therapies, assays, devices, or procedures for diagnosing or treating diseases. Additionally, clinicians, who make use of research outputs to evaluate patient health or administer therapy in various clinical settings and healthcare contexts, are also part of the target audience.