Exploring the mechanical and biological properties of a resin-ceramic composite with biomimetic nacre structure containing zinc used for prosthodontics

IF 3.3 2区医学 Q2 ENGINEERING, BIOMEDICAL

Journal of the Mechanical Behavior of Biomedical Materials Pub Date : 2024-11-05 DOI:10.1016/j.jmbbm.2024.106799

Zhongheng Yang , Sen Zhang , Mingfeng Wang , Jiao Yan , Tao Yan , Zengqian Liu , Qiang Wang , Zhe Yi , Yuzhong Gao

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引用次数: 0

Abstract

Enhancement of the mechanical and biological properties of dental restoration materials is of significant importance. Drawing inspiration from the architecture and mechanical properties of natural nacre, we employed a low-cost accumulative rolling process to develop resin-ceramic composites with suitable hardness and high toughness. Plate-like aluminum oxide powder with diameters of 5–10 μm and nano-zinc oxide (ZnO) with antibacterial properties were mixed as the ceramic phase of the composite. Aluminum oxide ceramic plates were stacked using an accumulative rolling process to achieve a consistent orientation, followed by sintering to obtain porous ceramic scaffolds. The ceramic scaffolds were subsequently immersed in methyl methacrylate resin to complete the fabrication of the biomimetic composites. The mechanical and biological properties of the composites were comprehensively tested. The composites had a suitable hardness (1.09–1.63 GPa), excellent flexural strength (156.7–167.8 MPa), and fracture toughness (K_IC = 2.66–3.59 MPa m^1/2). Biomimetic composites are expected to mitigate the wear of natural teeth without developing fractures or deformations, while also exhibiting excellent cytocompatibility and antibacterial activity. This study investigated the factors influencing crack propagation in fracture tests and provided insights into enhancing the toughness of dental restorative materials. The biomimetic resin-ceramic composites containing Zn developed in this study have the potential to be used as functional dental restoration materials.

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探索含锌的仿生物珍珠岩结构树脂陶瓷复合材料在修复牙科中的机械和生物特性。

提高牙科修复材料的机械和生物特性具有重要意义。我们从天然珍珠质的结构和机械性能中汲取灵感，采用低成本的累积轧制工艺，开发出具有合适硬度和高韧性的树脂陶瓷复合材料。直径为 5-10 μm 的板状氧化铝粉末与具有抗菌性能的纳米氧化锌（ZnO）混合，作为复合材料的陶瓷相。氧化铝陶瓷板采用累积轧制工艺堆叠，以获得一致的取向，然后进行烧结，以获得多孔陶瓷支架。随后将陶瓷支架浸入甲基丙烯酸甲酯树脂中，完成仿生物复合材料的制造。对复合材料的机械和生物特性进行了全面测试。复合材料具有合适的硬度（1.09-1.63 GPa）、优异的抗弯强度（156.7-167.8 MPa）和断裂韧性（KIC = 2.66-3.59 MPa m1/2）。仿生复合材料有望减轻天然牙齿的磨损，而不会产生断裂或变形，同时还能表现出优异的细胞相容性和抗菌活性。本研究调查了影响断裂试验中裂纹扩展的因素，为提高牙科修复材料的韧性提供了见解。本研究开发的含锌生物仿生树脂陶瓷复合材料有望用作功能性牙科修复材料。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of the Mechanical Behavior of Biomedical Materials 工程技术-材料科学：生物材料

CiteScore

7.20

自引率

7.70%

发文量

505

审稿时长

46 days

期刊介绍： The Journal of the Mechanical Behavior of Biomedical Materials is concerned with the mechanical deformation, damage and failure under applied forces, of biological material (at the tissue, cellular and molecular levels) and of biomaterials, i.e. those materials which are designed to mimic or replace biological materials. The primary focus of the journal is the synthesis of materials science, biology, and medical and dental science. Reports of fundamental scientific investigations are welcome, as are articles concerned with the practical application of materials in medical devices. Both experimental and theoretical work is of interest; theoretical papers will normally include comparison of predictions with experimental data, though we recognize that this may not always be appropriate. The journal also publishes technical notes concerned with emerging experimental or theoretical techniques, letters to the editor and, by invitation, review articles and papers describing existing techniques for the benefit of an interdisciplinary readership.