[Age-associated dynamics in blood pressure and dispersion mapping of the electrocardiogram in comparison with the incidence of mortality from circulation system diseases in residents of Magadan.]

Abstract

This research assessed blood pressure and dispersion mapping in reliance on age (Myocardium and Rhythm indices), the incidence of their deviations from the standard values in comparison with the tendency in mortality from diseases of the blood circulation system. For this purpose, we studied test results of 602 men and 776 women (total 1 378 people) aged 17-90 years who permanently inhabited Magadan city and underwent medical examination in 2016-2019, and mortality rates from circulatory system diseases during this period were estimated. The research showed a strong link of the increasing age to the growth in the blood pressure variables, with hypertensive focus, and the deviations in the ECG dispersion characteristics of the Myocardium and Rhythm indices tended to grow bigger. Regardless of the subjective gender, the highest frequency of changes in the ECG dispersion mapping was observed owing to disorders in the atrial depolarization phase (G1-G2) and ventricular hypertrophy (G9). The incidence of deviations that showed changes in the repolarization of the myocardium of the right and left ventricles of the heart (G5-G6) proved to be more common in women than in men. The cumulative deviations in the G3-G4 and G5-G7 groups indicated that men experienced the development of myocardial ischemia in their 2nd middle age while women exhibited these symptoms later, in an older period of their ontogeny. The picture of the raised variables in blood pressure, Myocardium and Rhythm indices demonstrated the presence of gender-related differences from the normal standards which formed critical periods: in the 2nd middle stage of ontogeny in men, and in older age in women. A peak in mortality from cardiovascular failures in residents of Magadan tended to fall on the above periods of ontogeny. Resulting from the study, prevention activities must be given emphasis and further promoted as health state control methods in order to identify risks for the development of cardiovascular diseases in age-related patients.