Lingering impact: Maternal SARS-CoV-2 infection during early pregnancy results in fetal situs inversus.

IF 12.8 Q1 MEDICINE, RESEARCH & EXPERIMENTAL

Med Pub Date : 2024-11-08 DOI:10.1016/j.medj.2024.10.010

Kjersti M Aagaard, Alireza A Shamshirsaz

引用次数: 0

Abstract

In this issue of Med, Guo et al.¹ describe their observed association of maternal SARS-CoV-2 infection in early (4-6 weeks) pregnancy with a confirmed fetal diagnosis of situs inversus congenital heart disease. Using sophisticated genomic tools and population-based statistical modeling, the study's authors present a very convincing argument causally linking maternal SARS-CoV-2 infection and resultant fetal situs inversus.

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挥之不去的影响：孕早期母体感染 SARS-CoV-2 导致胎儿坐位不正。

在本期《医学》杂志上，Guo 等人1 描述了他们观察到的孕早期（4-6 周）母体感染 SARS-CoV-2 与胎儿确诊为坐位性先天性心脏病之间的关联。该研究的作者利用先进的基因组学工具和基于人群的统计模型，提出了一个非常有说服力的论点，证明母体感染 SARS-CoV-2 与胎儿的坐位性先天性心脏病之间存在因果关系。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Med MEDICINE, RESEARCH & EXPERIMENTAL-

CiteScore

17.70

自引率

0.60%

发文量

102

期刊介绍： Med is a flagship medical journal published monthly by Cell Press, the global publisher of trusted and authoritative science journals including Cell, Cancer Cell, and Cell Reports Medicine. Our mission is to advance clinical research and practice by providing a communication forum for the publication of clinical trial results, innovative observations from longitudinal cohorts, and pioneering discoveries about disease mechanisms. The journal also encourages thought-leadership discussions among biomedical researchers, physicians, and other health scientists and stakeholders. Our goal is to improve health worldwide sustainably and ethically. Med publishes rigorously vetted original research and cutting-edge review and perspective articles on critical health issues globally and regionally. Our research section covers clinical case reports, first-in-human studies, large-scale clinical trials, population-based studies, as well as translational research work with the potential to change the course of medical research and improve clinical practice.