Unusual paralytic shellfish poisoning toxins in Cayuga Lake, New York

IF 2.6 4区医学 Q2 PHARMACOLOGY & PHARMACY

Toxicon Pub Date : 2024-11-07 DOI:10.1016/j.toxicon.2024.108165

Zacharias J. Smith , Gregory L. Boyer

引用次数: 0

Abstract

Cyanobacteria blooms were detected in 2017 and 2018 in Cayuga Lake, New York, with paralytic shellfish poisoning toxins (PSPTs) the primary toxin detected. Analysis of these samples by HPLC with chemical oxidation, receptor binding assay, ELISA, and LC-MS/MS confirmed the presence of PSPTs but each method gave highly unusual results based on the theory establishing each method. The structures of the toxins could not be identified and may be ‘unusual’ or unelucidated PSPTs.

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纽约卡尤加湖中的异常麻痹性贝类中毒毒素。

2017 年和 2018 年，纽约州卡尤加湖检测到蓝藻藻华，其中麻痹性贝类中毒毒素（PSPTs）是检测到的主要毒素。通过 HPLC 化学氧化法、受体结合测定法、ELISA 和 LC-MS/MS 对这些样本进行分析，证实了 PSPTs 的存在，但根据每种方法的理论基础，每种方法都得出了极不寻常的结果。这些毒素的结构无法确定，可能是 "不常见的 "或未阐明的 PSPT。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Toxicon 医学-毒理学

CiteScore

4.80

自引率

10.70%

发文量

358

审稿时长

68 days

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