Fellow Eye Risk of Rhegmatogenous Retinal Detachment in the United States: IRIS Registry (Intelligent Research in Sight) Analysis.

IF 0.9 4区医学 Q4 OPHTHALMOLOGY

Ophthalmic surgery, lasers & imaging retina Pub Date : 2024-11-01 DOI:10.3928/23258160-20240927-02

Ahmad Al-Moujahed, Alexander Ivanov, William Kearney, Nathan Hall, Connor Ross, Tobias Elze, Lucia Sobrin, Joan W Miller, Alice Lorch, John B Miller, Dan Gong

{"title":"Fellow Eye Risk of Rhegmatogenous Retinal Detachment in the United States: IRIS Registry (Intelligent Research in Sight) Analysis.","authors":"Ahmad Al-Moujahed, Alexander Ivanov, William Kearney, Nathan Hall, Connor Ross, Tobias Elze, Lucia Sobrin, Joan W Miller, Alice Lorch, John B Miller, Dan Gong","doi":"10.3928/23258160-20240927-02","DOIUrl":null,"url":null,"abstract":"Background and objective: This study aimed to investigate the rate of rhegmatogenous retinal detachment (RRD) in the fellow eye of patients after developing an RRD in one eye.Patients and methods: This is a retrospective cohort study of patients with a new RRD diagnosis in the American Academy of Ophthalmology IRIS Registry (Intelligent Research in Sight) from 2016 to 2020. The association between risk factors of RRD and fellow-eye RRD was evaluated using Cox regression.Results: Among the 201,622 patients who developed a new RRD in at least one eye, 6,740 (3.34%) developed an RRD in the fellow eye at a mean time of 406.02 days (SD = 373.74) from the first eye diagnosis. Of those 6,740 eyes, 1,889 (28.03%) had lattice degeneration, 3,938 (58.43%) had PVD, 588 (8.72%) had cataract surgery, and 38 (0.56%) had complex cataract surgery. Adjusted regression modeling showed that male sex (HR 1.73, [95% confidence interval (CI) 1.64 to 1.83]; P < 0.001), younger age at first eye RRD diagnosis (HR 1.02, [95% CI 1.01 to 1.02]; P < 0.001), active smoking (HR 1.13, [95% CI 1.05 to 1.22]; P = 0.002), and cataract surgery (HR 1.33, [95% CI 1.23 to 1.45]; P < 0.001) were associated with increased risk of a fellow eye RRD. On the other hand, fellow eye PVD was associated with a lower risk of RRD (HR 0.80, [95% CI 0.76 to 0.84]; P < 0.001).Conclusion: Among patients with an RRD in one eye, male sex, younger age of first eye RRD diagnosis, active smoking, and cataract surgery were associated with a higher risk of developing a fellow eye RRD, whereas fellow eye PVD was associated with a lower risk of fellow eye RRD. [Ophthalmic Surg Lasers Imaging Retina 2024;55:XX-XX.].","PeriodicalId":19679,"journal":{"name":"Ophthalmic surgery, lasers & imaging retina","volume":" ","pages":"1-5"},"PeriodicalIF":0.9000,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Ophthalmic surgery, lasers & imaging retina","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.3928/23258160-20240927-02","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"OPHTHALMOLOGY","Score":null,"Total":0}

引用次数: 0

Abstract

Background and objective: This study aimed to investigate the rate of rhegmatogenous retinal detachment (RRD) in the fellow eye of patients after developing an RRD in one eye.

Patients and methods: This is a retrospective cohort study of patients with a new RRD diagnosis in the American Academy of Ophthalmology IRIS Registry (Intelligent Research in Sight) from 2016 to 2020. The association between risk factors of RRD and fellow-eye RRD was evaluated using Cox regression.

Results: Among the 201,622 patients who developed a new RRD in at least one eye, 6,740 (3.34%) developed an RRD in the fellow eye at a mean time of 406.02 days (SD = 373.74) from the first eye diagnosis. Of those 6,740 eyes, 1,889 (28.03%) had lattice degeneration, 3,938 (58.43%) had PVD, 588 (8.72%) had cataract surgery, and 38 (0.56%) had complex cataract surgery. Adjusted regression modeling showed that male sex (HR 1.73, [95% confidence interval (CI) 1.64 to 1.83]; P < 0.001), younger age at first eye RRD diagnosis (HR 1.02, [95% CI 1.01 to 1.02]; P < 0.001), active smoking (HR 1.13, [95% CI 1.05 to 1.22]; P = 0.002), and cataract surgery (HR 1.33, [95% CI 1.23 to 1.45]; P < 0.001) were associated with increased risk of a fellow eye RRD. On the other hand, fellow eye PVD was associated with a lower risk of RRD (HR 0.80, [95% CI 0.76 to 0.84]; P < 0.001).

Conclusion: Among patients with an RRD in one eye, male sex, younger age of first eye RRD diagnosis, active smoking, and cataract surgery were associated with a higher risk of developing a fellow eye RRD, whereas fellow eye PVD was associated with a lower risk of fellow eye RRD. [Ophthalmic Surg Lasers Imaging Retina 2024;55:XX-XX.].

查看原文本刊更多论文

美国同胞眼部发生流变性视网膜脱离的风险：IRIS Registry（视力智能研究）分析。

背景和目的：本研究旨在调查单眼发生流变性视网膜脱离（RRD）后患者同侧眼的RRD发生率：这是一项回顾性队列研究，研究对象是2016年至2020年美国眼科学会IRIS注册中心（Intelligent Research in Sight）新诊断出RRD的患者。采用Cox回归法评估了RRD风险因素与同眼RRD之间的关联：结果：在 201622 名至少一只眼睛出现新 RRD 的患者中，有 6740 名（3.34%）患者的同侧眼睛出现 RRD，距离第一只眼睛确诊的平均时间为 406.02 天（SD = 373.74）。在这6740只眼睛中，1889只（28.03%）患有晶状体变性，3938只（58.43%）患有PVD，588只（8.72%）接受过白内障手术，38只（0.56%）接受过复杂白内障手术。调整后的回归模型显示，男性（HR 1.73，[95% 置信区间 (CI) 1.64 至 1.83]；P < 0.001）、第一眼 RRD 诊断年龄较小（HR 1.02，[95% CI 1.01 至 1.02]；P < 0.001）、主动吸烟（HR 1.13，[95% CI 1.05 至 1.22]；P = 0.002）和白内障手术（HR 1.33，[95% CI 1.23 至 1.45]；P < 0.001）与同眼 RRD 风险增加有关。另一方面，同侧眼PVD与较低的RRD风险相关（HR 0.80，[95% CI 0.76至0.84]；P <0.001）：结论：在单眼RRD患者中，男性、第一眼RRD诊断年龄较小、主动吸烟和白内障手术与较高的同眼RRD风险相关，而同眼PVD与较低的同眼RRD风险相关。[眼科手术激光成像视网膜2024;55:XX-XX]。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Ophthalmic surgery, lasers & imaging retina OPHTHALMOLOGY-SURGERY

CiteScore

1.80

自引率

0.00%

发文量

期刊介绍： OSLI Retina focuses exclusively on retinal diseases, surgery and pharmacotherapy. OSLI Retina will offer an expedited submission to publication effort of peer-reviewed clinical science and case report articles. The front of the journal offers practical clinical and practice management features and columns specific to retina specialists. In sum, readers will find important peer-reviewed retina articles and the latest findings in techniques and science, as well as informative business and practice management features in one journal.