Risk of uveitis among E-Cigarette Users: a multi-institutional TriNetX study.

Abstract

Purpose: To determine the risk of uveitis among e-cigarette users METHODS: The TriNetX database was used to recruit adult patients with and without a history of e-cigarette usage. The primary outcome was the incidence of new-onset uveitis.

Results: E-cigarette users were associated with an increased risk for uveitis compared to non-users (HR: 2.53, CI: 2.33-2.76). Subgroup analysis revealed an increased risk of uveitis among e-cigarette users aged 18-39 years (HR: 2.59, CI: 2.11-3.17), 40-64 years (HR: 2.20, CI: 1.95-2.48) and ≥65 years (HR: 3.15, CI: 2.72-3.64).

Conclusions: An increased risk for uveitis was seen among e-cigarette users compared to non-users.