The Frequency of Meal-Replacement Products Drinking and All-Cause, CVD, and Cancer Mortality.

IF 4.8 2区医学 Q1 NUTRITION & DIETETICS

Nutrients Pub Date : 2024-11-02 DOI:10.3390/nu16213770

Yuxuan Zhao, Aolin Li, Haiming Yang, Meng Xiao, Mingyu Song, Zilun Shao, Rong Jiao, Yuanjie Pang, Wenjing Gao, Tao Huang, Jun Lv, Liming Li, Canqing Yu, Dianjianyi Sun

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引用次数: 0

Abstract

Objectives: Our study aimed to assess the associations between meal-replacement (MR) drinking and risks of all-cause, cardiovascular and cerebrovascular disease (CVD), and cancer mortality.

Methods: The study was based on 6770 adults aged 20 years or older from the National Health and Nutrition Examination (NHANES) 2003-2006 with linked mortality data from the National Death Index for linked mortality records (until 31 December 2019). Respondents were categorized into four groups according to the frequency of MR drinking: ≤1 time per month (seldom), 2-3 times per month (monthly), 1-6 times per week (weekly), and ≥1 time per day (daily). The adjusted hazard ratios (aHRs) of MR drinking with all-cause, CVD, and cancer mortality were estimated by Cox proportional hazards regression models. Likelihood ratio tests were used to find potential interactions of MR drinking with age, sex, and BMI.

Results: During a median follow-up of 14.4 years, a total of 1668 death events were recorded among the study population. Compared to respondents who seldom drank MR, daily and weekly drinkers had greater risks of all-cause mortality (aHRs and 95% confidence intervals [CI]: 1.52 [1.17-1.97] for daily; 1.54 [1.24-1.91] for weekly). Stratified analyses indicated that the effects of MR on all-cause mortality were different between females and males and were more substantial among females (P for interaction: 0.003; daily female drinkers vs. daily male drinkers: 2.01 [1.40-2.90] vs. 1.24 [0.85-1.81]; weekly female drinkers vs. weekly male drinkers: 1.68 [1.26-2.24] vs. 1.36 [0.97-1.91]).

Conclusions: Daily and weekly MR drinking might increase the risk of all-cause mortality.

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代餐产品的饮用频率与全因、心血管疾病和癌症死亡率。

研究目的我们的研究旨在评估代餐饮品（MR）与全因、心脑血管疾病（CVD）和癌症死亡风险之间的关联：研究对象是美国国家健康与营养调查（NHANES）2003-2006年的6770名20岁或20岁以上的成年人，他们的死亡数据来自美国国家死亡指数（National Death Index）的相关死亡记录（截至2019年12月31日）。根据MR饮酒频率将受访者分为四组：每月≤1次（很少）、每月2-3次（每月）、每周1-6次（每周）和每天≥1次（每天）。MR饮酒与全因死亡率、心血管疾病死亡率和癌症死亡率的调整后危险比（aHRs）由Cox比例危险回归模型估算得出。似然比检验用于发现MR饮酒与年龄、性别和体重指数的潜在交互作用：结果：在中位数为 14.4 年的随访期间，研究人群共记录了 1668 例死亡事件。与很少饮用 MR 的受访者相比，每天和每周饮用者的全因死亡风险更高（aHRs 和 95% 置信区间 [CI]：1.52 [1.17-1.17] ）：每日饮酒者为 1.52 [1.17-1.97]；每周饮酒者为 1.54 [1.24-1.91]）。分层分析表明，MR 对全因死亡率的影响在女性和男性之间存在差异，在女性中的影响更大（交互作用的 P. 0.003；每日饮酒的女性对全因死亡率的影响更大，而每周饮酒的女性对全因死亡率的影响更大）：0.003；每天饮酒的女性与每天饮酒的男性相比：2.01 [1.40-2.90] vs. 1.24 [0.85-1.81]；每周饮酒的女性与每周饮酒的男性相比：1.68 [1.26-2.90] vs. 1.24 [0.85-1.81]：1.68[1.26-2.24]vs.1.36[0.97-1.91]）：结论：每日和每周MR饮酒可能会增加全因死亡风险。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Nutrients NUTRITION & DIETETICS-

CiteScore

9.20

自引率

15.30%

发文量

4599

审稿时长

16.74 days

期刊介绍： Nutrients (ISSN 2072-6643) is an international, peer-reviewed open access advanced forum for studies related to Human Nutrition. It publishes reviews, regular research papers and short communications. Our aim is to encourage scientists to publish their experimental and theoretical results in as much detail as possible. There is no restriction on the length of the papers. The full experimental details must be provided so that the results can be reproduced.