Concurrent Guillain-Barre/acute transverse myelitis overlap syndrome after COVID-19 infection in a patient with ITP: A case report.

IF 1.3 4区医学 Q2 MEDICINE, GENERAL & INTERNAL

Medicine Pub Date : 2024-11-08 DOI:10.1097/MD.0000000000040346

Ruomeng Chen, Liang Wang, Binbin Wang, Xiujuan Song, Xiaoyun Liu

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引用次数: 0

Abstract

Rationale: Patients with chronic immune diseases, such as idiopathic thrombocytopenic purpura (ITP), should be alert for Guillain-Barre/acute transverse myelitis (GBS/ATM) overlap syndrome after infection with coronavirus disease 2019 (COVID-19).

Patient concerns: A 65-year-old male with an ITP history, who presented with limb numbness and weakness, urinary retention, right peripheral facial paralysis, and diplopia 2 weeks after being diagnosed with COVID-19.

Diagnosis: GBS/ATM overlap syndrome secondary to COVID-19.

Interventions: Five days intravenous immune globulin, methylprednisolone (500 mg) was added for treatment. He was discharged with medicine and continued to take Methylprednisolone tablets (60 mg/d), Eltrombopag olamine (25 mg 1/d), Mecobalamine tablets, vitamin B1, and rehabilitation treatment outside the hospital.

Outcomes: The patient significantly improved after initial treatment, he returned to normal life after 8 weeks. Five months later, he was infected with COVID-19 for the second time, exhibiting only symptoms of upper respiratory tract infection and no other discomfort.

Lessons: COVID-19 infection can lead to secondary myelitis and GBS, and GBS/ATM overlap syndrome is rare, but patients are significantly better after immunization and hormone therapy.

查看原文本刊更多论文

一名 ITP 患者感染 COVID-19 后并发格林-巴利综合征/急性横贯性脊髓炎重叠综合征：病例报告。

理论依据：特发性血小板减少性紫癜（ITP）等慢性免疫性疾病患者感染2019年冠状病毒病（COVID-19）后，应警惕格林-巴利/急性横贯性脊髓炎（GBS/ATM）重叠综合征：一名65岁的男性，有ITP病史，在确诊感染COVID-19两周后出现肢体麻木和无力、尿潴留、右侧外周面瘫和复视：继发于COVID-19的GBS/ATM重叠综合征：五天静脉注射免疫球蛋白，并加用甲基强的松龙（500 毫克）进行治疗。出院后继续服用甲泼尼龙片（60 mg/d）、艾曲波帕胺（25 mg 1/d）、甲钴胺片、维生素 B1，并在院外进行康复治疗：初步治疗后，患者病情明显好转，8 周后恢复正常生活。五个月后，他第二次感染 COVID-19，仅表现出上呼吸道感染症状，无其他不适：启示：COVID-19感染可导致继发性脊髓炎和GBS，GBS/ATM重叠综合征很少见，但患者在接受免疫和激素治疗后病情会明显好转。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Medicine 医学-医学：内科

CiteScore

2.80

自引率

0.00%

发文量

4342

审稿时长

>12 weeks

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