Evaluating the Economic and Epidemiological Impact of RSV Hospitalizations in Southern Austria [Southern Austria Respiratory Syncytial Virus INpatient Investigation (ARNI Study)]

IF 4.3 4区医学 Q1 INFECTIOUS DISEASES

Influenza and Other Respiratory Viruses Pub Date : 2024-11-13 DOI:10.1111/irv.70046

G. Sever Yildiz, E. Resch, V. Strenger, E. Eber, B. Resch

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引用次数: 0

Abstract

Objective

RSV bronchiolitis is a leading cause of hospitalization in infants and young children. We aimed to document the economic burden and epidemiology of RSV over seven seasons in Southern Austria.

Patients and Methods

All RSV-associated hospitalized (PCR-proven) children ≤ 5 years of age between 1 October 2015 and 30 April 2022 were collected retrospectively. Demographic and epidemiologic data, along with hospitalization costs (direct and indirect), were calculated.

Results

Among 976 children hospitalized due to RSV infection, 87% were healthy term infants, and 79% were < 12 months old. Prematurity (13%) and pre-existing conditions (11%) significantly impacted older children—59% of cases in the 2nd compared with 68% in the 1st year of live. RSV-related hospital costs were approximately €2.0 millions per year (of a total of 60 millions per year). RSV accounted for 19% of hospitalizations due to acute respiratory illness (ARI) in children ≤ 5 years, 37% of all ARI < 6 months, 28% of all ARI < 12 and 6.3% of all-cause hospitalizations < 12 months of age, respectively.

Conclusions

Every 5th hospitalization due to respiratory illness in children ≤ 5 years of age was associated with RSV, representing 7.9% of all hospitalizations and 3.3% of all paediatric hospitalization costs.

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评估奥地利南部 RSV 住院治疗的经济和流行病学影响 [奥地利南部呼吸道合胞病毒住院患者调查 (ARNI 研究)]。

目的：RSV 支气管炎是导致婴幼儿住院治疗的主要原因。我们旨在记录奥地利南部七个季节中 RSV 的经济负担和流行病学情况：我们回顾性地收集了 2015 年 10 月 1 日至 2022 年 4 月 30 日期间所有与 RSV 相关的 5 岁以下住院儿童（PCR 证实）。计算了人口统计学和流行病学数据以及住院费用（直接和间接）：在因感染 RSV 而住院的 976 名儿童中，87% 是健康的足月婴儿，79% 为结论：5岁以下儿童因呼吸道疾病住院的每5例中就有1例与RSV有关，占所有住院病例的7.9%，占所有儿科住院费用的3.3%。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Influenza and Other Respiratory Viruses 医学-病毒学

CiteScore

7.20

自引率

4.50%

发文量

120

审稿时长

6-12 weeks

期刊介绍： Influenza and Other Respiratory Viruses is the official journal of the International Society of Influenza and Other Respiratory Virus Diseases - an independent scientific professional society - dedicated to promoting the prevention, detection, treatment, and control of influenza and other respiratory virus diseases. Influenza and Other Respiratory Viruses is an Open Access journal. Copyright on any research article published by Influenza and Other Respiratory Viruses is retained by the author(s). Authors grant Wiley a license to publish the article and identify itself as the original publisher. Authors also grant any third party the right to use the article freely as long as its integrity is maintained and its original authors, citation details and publisher are identified.