Primary mesenchymal tumors of the prostate:¹⁸F FDG PET/CT findings.

IF 3.1 3区医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

EJNMMI Research Pub Date : 2024-11-14 DOI:10.1186/s13550-024-01177-4

Zihao Tao, Yongkang Qiu, Zhao Chen, Wenpeng Huang, Lele Song, Aixiang Wang, Xuesong Li, Lei Kang

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引用次数: 0

Abstract

Background: Primary mesenchymal tumors of the prostate are very rare, and there is no systematic report on fluorine-18-fluorodeoxyglucose positron emission tomography (¹⁸F-FDG PET/CT). The aim of this research was to characterize mesenchymal tumors of the prostate on ¹⁸F-FDG PET/CT.

Results: We included 13 patients with pathologically confirmed mesenchymal neoplasms of the prostate. The location, size, maximum standardized uptake value (SUVmax), metabolic tumor volume (MTV), total glycolysis of the lesion (TLG), pathologic findings, and available imaging study of the tumors were reviewed. Of the 13 patients (median age, 38 years; ranged from 13 to 74 years), the mean size of the tumors was 8.8 cm in diameter ranged from 5 to 16.1 cm. SUVmax ranged from 3.1 to 17.6 (mean 9.5), MTV ranged from 4.9 to 398 cm³ (mean 109 cm³) and TLG ranged from 21.3 to 1216 g (mean 96 g). The seminal vesicles, rectum, and bladder are the most commonly affected sites of invasion, while metastasis typically occurs in the bones, lungs, and lymph nodes.

Conclusions: Mesenchymal tumors of the prostate revealed large sizes and high SUVmax, MTV and TLG levels on ¹⁸F-FDG PET/CT. ¹⁸F-FDG PET/CT may be useful for accurate diagnosis, staging, and restaging, which plays an important role in the management of subsequent plans.

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前列腺原发性间质瘤：18F FDG PET/CT 发现。

背景：前列腺原发性间质瘤非常罕见，目前还没有关于氟-18-氟脱氧葡萄糖正电子发射断层扫描（18F-FDG PET/CT）的系统报告。本研究旨在通过 18F-FDG PET/CT 分析前列腺间质瘤的特征：结果：我们纳入了 13 例经病理证实的前列腺间质肿瘤患者。我们回顾了肿瘤的位置、大小、最大标准化摄取值（SUVmax）、代谢肿瘤体积（MTV）、病变总糖酵解率（TLG）、病理结果以及现有的影像学研究。13 名患者（中位年龄为 38 岁，13 至 74 岁不等）的肿瘤平均直径为 8.8 厘米，5 至 16.1 厘米不等。SUVmax 为 3.1 至 17.6（平均为 9.5），MTV 为 4.9 至 398 立方厘米（平均为 109 立方厘米），TLG 为 21.3 至 1216 克（平均为 96 克）。精囊、直肠和膀胱是最常见的侵犯部位，而转移通常发生在骨骼、肺部和淋巴结：结论：前列腺间质瘤体积大，18F-FDG PET/CT 显示的 SUVmax、MTV 和 TLG 水平高。18F-FDG PET/CT 可用于准确诊断、分期和再分期，在后续计划的管理中发挥重要作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

EJNMMI Research RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING&nb-

CiteScore

5.90

自引率

3.10%

发文量

审稿时长

13 weeks

期刊介绍： EJNMMI Research publishes new basic, translational and clinical research in the field of nuclear medicine and molecular imaging. Regular features include original research articles, rapid communication of preliminary data on innovative research, interesting case reports, editorials, and letters to the editor. Educational articles on basic sciences, fundamental aspects and controversy related to pre-clinical and clinical research or ethical aspects of research are also welcome. Timely reviews provide updates on current applications, issues in imaging research and translational aspects of nuclear medicine and molecular imaging technologies. The main emphasis is placed on the development of targeted imaging with radiopharmaceuticals within the broader context of molecular probes to enhance understanding and characterisation of the complex biological processes underlying disease and to develop, test and guide new treatment modalities, including radionuclide therapy.