Clinical and Patient-Reported Outcome Measures of Palatal Donor Site Healing Using Polyvinylpyrrolidone–Sodium Hyaluronate Gel as a Dressing Material Following Free Gingival Graft Harvesting: A Randomized Controlled Clinical Trial

IF 1.7 Q3 DENTISTRY, ORAL SURGERY & MEDICINE

Clinical and Experimental Dental Research Pub Date : 2024-11-11 DOI:10.1002/cre2.70026

Mohammad Baroudi, Majd Othman

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引用次数: 0

Abstract

Objectives

This study evaluates the efficacy of polyvinylpyrrolidone–sodium hyaluronate (PVP-SH) gel as a dressing material in enhancing both clinical and patient-reported outcomes post-free gingival graft (FGG) harvesting from the hard palate.

Material and Methods

This randomized clinical trial included 18 patients and spanned from June 2022 to August 2023. Patients received an FGG procedure to manage a lack of attached gingiva. Following graft harvesting, patients were divided into two groups: the control group, which received Coe-Pak, and the test group, which was treated with PVP-SH gel. The primary outcome measured was complete epithelialization. Secondary outcomes included the Landry healing scale, post-operative pain level, and patient willingness to receive the same treatment again.

Results

The test group reported significantly lower analgesic use (p < 0.001) and reduced pain severity (p < 0.001) compared to the control group. Furthermore, test group patients indicated a higher level of satisfaction regarding the prospect of retreatment. In contrast, the control group showed significantly slower progress in wound healing and epithelization (p < 0.05) compared to the test group.

Conclusions

The findings of this study suggest that PVP-SH gel is a superior dressing material post-FGG harvesting, yielding improved clinical and patient-reported outcomes relative to Coe-Pak.

Abstract Image

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使用聚乙烯吡咯烷酮-透明质酸钠凝胶作为游离龈移植取材后腭供体部位愈合的临床和患者报告结果测量：随机对照临床试验。

研究目的本研究评估了聚乙烯吡咯烷酮-透明质酸钠（PVP-SH）凝胶作为敷料在提高硬腭无龈移植（FGG）术后临床和患者报告结果方面的疗效：这项随机临床试验包括18名患者，时间跨度为2022年6月至2023年8月。患者接受 FGG 手术治疗附着龈缺失。移植物采集后，患者被分为两组：对照组（接受 Coe-Pak 治疗）和试验组（接受 PVP-SH 凝胶治疗）。测量的主要结果是完全上皮化。次要结果包括兰德里愈合量表、术后疼痛程度和患者再次接受相同治疗的意愿：结果：试验组的镇痛剂用量明显降低（p 结论：试验组的镇痛剂用量明显降低：本研究的结果表明，PVP-SH 凝胶是 FGG 切除术后的一种优质敷料，与 Coe-Pak 相比，PVP-SH 凝胶可改善临床和患者报告的结果。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical and Experimental Dental Research DENTISTRY, ORAL SURGERY & MEDICINE-

CiteScore

3.30

自引率

5.60%

发文量

165

审稿时长

26 weeks

期刊介绍： Clinical and Experimental Dental Research aims to provide open access peer-reviewed publications of high scientific quality representing original clinical, diagnostic or experimental work within all disciplines and fields of oral medicine and dentistry. The scope of Clinical and Experimental Dental Research comprises original research material on the anatomy, physiology and pathology of oro-facial, oro-pharyngeal and maxillofacial tissues, and functions and dysfunctions within the stomatognathic system, and the epidemiology, aetiology, prevention, diagnosis, prognosis and therapy of diseases and conditions that have an effect on the homeostasis of the mouth, jaws, and closely associated structures, as well as the healing and regeneration and the clinical aspects of replacement of hard and soft tissues with biomaterials, and the rehabilitation of stomatognathic functions. Studies that bring new knowledge on how to advance health on the individual or public health levels, including interactions between oral and general health and ill-health are welcome.