Duloxetine-induced syndrome of inappropriate antidiuretic hormone secretion in a patient with neuropathic pain

IF 0.6 Q3 MEDICINE, GENERAL & INTERNAL
Nobuyuki Takahashi, Yukiko Mori, Kenji Momo, Hidetomo Murakami, Hironori Tanaka
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引用次数: 0

Abstract

Syndrome of inappropriate antidiuretic hormone secretion (SIADH) induces hyponatremia accompanied by uric acid reduction. We report a case of a patient with small-cell lung cancer who developed SIADH with hypouricemia after duloxetine treatment and discuss the potential underlying mechanisms. SIADH and hypouricemia improved after duloxetine was switched to mirogabalin.

Abstract Image

一名神经病理性疼痛患者由度洛西汀诱发的抗利尿激素分泌失调综合征。
抗利尿激素分泌失调综合征(SIADH)会诱发低钠血症,并伴有尿酸降低。我们报告了一例小细胞肺癌患者在接受度洛西汀治疗后出现 SIADH 并伴有低尿酸血症的病例,并讨论了潜在的内在机制。将度洛西汀换成米罗卡宾后,SIADH 和低尿酸血症得到了改善。
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来源期刊
Clinical Case Reports
Clinical Case Reports MEDICINE, GENERAL & INTERNAL-
自引率
14.30%
发文量
1268
审稿时长
13 weeks
期刊介绍: Clinical Case Reports is different from other case report journals. Our aim is to directly improve global health and increase clinical understanding using case reports to convey important best practice information. We welcome case reports from all areas of Medicine, Nursing, Dentistry, and Veterinary Science and may include: -Any clinical case or procedure which illustrates an important best practice teaching message -Any clinical case or procedure which illustrates the appropriate use of an important clinical guideline or systematic review. As well as: -The management of novel or very uncommon diseases -A common disease presenting in an uncommon way -An uncommon disease masquerading as something more common -Cases which expand understanding of disease pathogenesis -Cases where the teaching point is based on an error -Cases which allow us to re-think established medical lore -Unreported adverse effects of interventions (drug, procedural, or other).
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