Bacterial small RNA makes a big impact for gut colonization

IF 20.6 1区医学 Q1 MICROBIOLOGY

Cell host & microbe Pub Date : 2024-11-13 DOI:10.1016/j.chom.2024.10.010

Elena Monzel, Mahesh S. Desai

引用次数: 0

Abstract

The functions of non-coding small RNAs (sRNAs) within the human microbiome remain largely unexplored. In this Cell Host & Microbe issue, El Mouali et al. identify Segatella RNA colonization factor (SrcF), a sRNA from a prevalent gut bacterium Segatella copri. SrcF promotes colonization of S. copri by regulating bacterial degradation of complex dietary carbohydrates.

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细菌小核糖核酸对肠道定植产生重大影响

人类微生物组中的非编码小 RNA（sRNA）的功能在很大程度上仍未得到探索。在本期《细胞-宿主-微生物》（Cell Host & Microbe）杂志中，El Mouali 等人发现了 Segatella RNA 定殖因子（SrcF），这是一种来自肠道流行细菌 Segatella copri 的 sRNA。SrcF 通过调节细菌对复杂食物碳水化合物的降解来促进 S. copri 的定植。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Cell host & microbe 生物-微生物学

CiteScore

45.10

自引率

1.70%

发文量

201

审稿时长

4-8 weeks

期刊介绍： Cell Host & Microbe is a scientific journal that was launched in March 2007. The journal aims to provide a platform for scientists to exchange ideas and concepts related to the study of microbes and their interaction with host organisms at a molecular, cellular, and immune level. It publishes novel findings on a wide range of microorganisms including bacteria, fungi, parasites, and viruses. The journal focuses on the interface between the microbe and its host, whether the host is a vertebrate, invertebrate, or plant, and whether the microbe is pathogenic, non-pathogenic, or commensal. The integrated study of microbes and their interactions with each other, their host, and the cellular environment they inhabit is a unifying theme of the journal. The published work in Cell Host & Microbe is expected to be of exceptional significance within its field and also of interest to researchers in other areas. In addition to primary research articles, the journal features expert analysis, commentary, and reviews on current topics of interest in the field.