Schizophrenia – new treatments soon

Jeremy Hall
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Abstract

Antipsychotic medications targeting dopamine receptors were identified 70 years ago. Recent clinical trials have shown that agonists of muscarinic acetylcholinergic receptors can improve both psychotic and negative symptoms in schizophrenia. Here, this new approach to the treatment of schizophrenia is reviewed in anticipation of the drugs being licensed clinically.

精神分裂症--新疗法即将问世
针对多巴胺受体的抗精神病药物在 70 年前就已被发现。最近的临床试验表明,毒蕈碱乙酰胆碱能受体激动剂可以改善精神分裂症患者的精神症状和阴性症状。在此,我们将对这种治疗精神分裂症的新方法进行回顾,以期待这些药物获得临床许可。
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