Efficient Route to N-Substituted β-Amido Ketone Scaffold Using Bismuth Nitrate-Catalyzed One-Pot MCR Protocol

IF 0.8 4区 化学 Q4 CHEMISTRY, ORGANIC
K. S. Sini, S. Arun, V. S. Shinu
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引用次数: 0

Abstract

A new catalytic one-pot synthesis of N-substituted β-amido carbonyl compounds has been developed using bismuth nitrate as highly efficient, commercially available, recyclable, and reusable acid catalyst. The efficiency of the proposed protocol was demonstrated by 17 examples including various functionalized N-substituted β-amido carbonyl compounds. The reaction utilized easily available and cost-effective starting materials and proceeded at room temperature in a short period of time, followed by aqueous workup.

Abstract Image

利用硝酸铋催化的一锅 MCR 程序制备 N-取代的 β-氨基酮支架的高效路线
利用硝酸铋作为高效、市售、可回收和可重复使用的酸催化剂,开发了一种新的催化一锅合成 N-取代的 β-氨基羰基化合物的方法。包括各种官能化 N-取代的 β-氨基羰基化合物在内的 17 个实例证明了所提方案的高效性。该反应利用了易于获得且成本效益高的起始材料,在室温下短时间内完成,随后进行水性处理。
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来源期刊
CiteScore
1.40
自引率
25.00%
发文量
139
审稿时长
3-6 weeks
期刊介绍: Russian Journal of Organic Chemistry is an international peer reviewed journal that covers all aspects of modern organic chemistry including organic synthesis, theoretical organic chemistry, structure and mechanism, and the application of organometallic compounds in organic synthesis.
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