Association between residential greenness exposure and semen quality: A retrospective study in China

IF 10.3 1区环境科学与生态学 Q1 ENVIRONMENTAL SCIENCES

Environment International Pub Date : 2024-11-01 DOI:10.1016/j.envint.2024.109132

Xuchao Dai , Weikang Chen , Guangyuan Liu , Feidi Li , Shuren Sun , Qi Chen , Gang Chen , Mengqi Zhang , Zhenfeng Wang , Wenyuan Li , Hong Huang , Jingping Li

{"title":"Association between residential greenness exposure and semen quality: A retrospective study in China","authors":"Xuchao Dai , Weikang Chen , Guangyuan Liu , Feidi Li , Shuren Sun , Qi Chen , Gang Chen , Mengqi Zhang , Zhenfeng Wang , Wenyuan Li , Hong Huang , Jingping Li","doi":"10.1016/j.envint.2024.109132","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><div>The association between greenness exposure and semen quality and the underlying mechanism are unclear.</div></div><div><h3>Objectives</h3><div>To assess the association between greenness exposure and semen quality and whether the association is mediated by air pollutant exposure.</div></div><div><h3>Methods</h3><div>We collected data from 10,273 men in Zhejiang, China, whose wives received assisted reproductive technology from 2015 to 2021. The mean exposure concentrations of air pollutants and greenness indices (normalized difference vegetation index (NDVI) and the soil-adjusted vegetation index (SAVI)) in the 300 m, 400 m, 800 m, and 1000 m buffer zones were assessed from 0–90 days prior to semen testing on the basis of the patient’s residential address. A multivariate linear mixed-effects model was used to evaluate the associations, and mediation analysis was used to investigate the influences of air pollutant exposure and body mass index (BMI) on the associations.</div></div><div><h3>Results</h3><div>The average (standard deviation) age of the participants was 33.1 (5.2) years. After adjusting for confounders, progressive motility was positively associated with the NDVI<sub>400m</sub> (β (95 % CI): 1.744 (0.834, 2.655)) and SAVI<sub>400m</sub> (β (95 % CI): 1.484 (0.591, 2.377)). Furthermore, we found that NO<sub>2</sub> and CO exposure significantly mediated part of the association between greenness exposure and progressive motility. Similar results are observed in the sensitivity analysis.</div></div><div><h3>Conclusions</h3><div>Our results suggest that greater greenness exposure is associated with higher semen quality and can be partially mediated by lower NO<sub>2</sub> and CO exposure levels.</div></div>","PeriodicalId":308,"journal":{"name":"Environment International","volume":"193 ","pages":"Article 109132"},"PeriodicalIF":10.3000,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Environment International","FirstCategoryId":"93","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0160412024007189","RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"ENVIRONMENTAL SCIENCES","Score":null,"Total":0}

引用次数: 0

Abstract

Background

The association between greenness exposure and semen quality and the underlying mechanism are unclear.

Objectives

To assess the association between greenness exposure and semen quality and whether the association is mediated by air pollutant exposure.

Methods

We collected data from 10,273 men in Zhejiang, China, whose wives received assisted reproductive technology from 2015 to 2021. The mean exposure concentrations of air pollutants and greenness indices (normalized difference vegetation index (NDVI) and the soil-adjusted vegetation index (SAVI)) in the 300 m, 400 m, 800 m, and 1000 m buffer zones were assessed from 0–90 days prior to semen testing on the basis of the patient’s residential address. A multivariate linear mixed-effects model was used to evaluate the associations, and mediation analysis was used to investigate the influences of air pollutant exposure and body mass index (BMI) on the associations.

Results

The average (standard deviation) age of the participants was 33.1 (5.2) years. After adjusting for confounders, progressive motility was positively associated with the NDVI_400m (β (95 % CI): 1.744 (0.834, 2.655)) and SAVI_400m (β (95 % CI): 1.484 (0.591, 2.377)). Furthermore, we found that NO₂ and CO exposure significantly mediated part of the association between greenness exposure and progressive motility. Similar results are observed in the sensitivity analysis.

Conclusions

Our results suggest that greater greenness exposure is associated with higher semen quality and can be partially mediated by lower NO₂ and CO exposure levels.

查看原文本刊更多论文

居住区绿化暴露与精液质量的关系：中国的一项回顾性研究

背景绿化暴露与精液质量之间的关系及其内在机制尚不清楚。目的评估绿化暴露与精液质量之间的关系，以及这种关系是否由空气污染物暴露介导。根据患者的居住地址，评估了精液检测前0-90天内300米、400米、800米和1000米缓冲区内的空气污染物平均暴露浓度和绿度指数（归一化差异植被指数（NDVI）和土壤调整植被指数（SAVI））。采用多变量线性混合效应模型评估相关性，并采用中介分析法研究空气污染物暴露和体重指数（BMI）对相关性的影响。在对混杂因素进行调整后，进行性运动与 NDVI400m (β (95 % CI): 1.744 (0.834, 2.655)) 和 SAVI400m (β (95 % CI): 1.484 (0.591, 2.377)) 呈正相关。此外，我们还发现，二氧化氮和一氧化碳暴露在很大程度上介导了绿度暴露与进行性运动之间的部分关联。结论我们的研究结果表明，更多的绿色暴露与更高的精液质量相关，而较低的二氧化氮和一氧化碳暴露水平可以在一定程度上起到中介作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Environment International 环境科学-环境科学

CiteScore

21.90

自引率

3.40%

发文量

734

审稿时长

2.8 months

期刊介绍： Environmental Health publishes manuscripts focusing on critical aspects of environmental and occupational medicine, including studies in toxicology and epidemiology, to illuminate the human health implications of exposure to environmental hazards. The journal adopts an open-access model and practices open peer review. It caters to scientists and practitioners across all environmental science domains, directly or indirectly impacting human health and well-being. With a commitment to enhancing the prevention of environmentally-related health risks, Environmental Health serves as a public health journal for the community and scientists engaged in matters of public health significance concerning the environment.