Epidemiological and anatomopathological profile of colorectal cancer in Northern Morocco between 2017 and 2019.

IF 1.1 4区 医学 Q4 GASTROENTEROLOGY & HEPATOLOGY
Mouade El Bali, Mohamed Mesmoudi, Amale Essayah, Kenza Arbai, Naima Ghailani Nourouti, Amina Barakat, Nabila Sellal, Mohcine Bennani Mechita
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引用次数: 0

Abstract

Background and study aims: Colorectal cancer (CRC) is the third most common type of cancer worldwide and the second leading cause of cancer-related death. CRC represents a major public health problem in many countries, and its incidence is increasing worldwide. In Morocco, CRC is the third most common cancer. However, epidemiological data on CRC in Morocco, especially in the north, are very limited. This study aimed to describe the epidemiological and clinicopathological characteristics of CRC in northern Morocco.

Patients and methods: This retrospective study was conducted at the Ahmed Ben Zayed Al Nahyan Regional Oncology Center of Tangier between April 2017 and December 2019. Data were collected from the medical records of confirmed CRC patients and analyzed using SPSS computer software version 23.

Results: CRC was detected in 142 patients, accounting for 13.0 % of all cancers identified during the study period in the center. The sex ratio (male/female) of all patients was 1.1. The mean age was 58 years, and the most affected group was 60-69 years old (29.0 %). The rectum was the most common anatomical site (44.0 %) compared to the left and right colon. Histologically, adenocarcinomas were the most common type (91.3 %), half of the tumors were moderately differentiated, and only 4.9 % of the patients presented with poorly differentiated tumors. At diagnosis, 83.0 % of patients were already in advanced stages (stage III, or IV), including 40.3 % presenting with metastatic disease. The liver (64.8 %) was the most affected site by metastasis in our series. Relapse was observed in 11.9 % of patients.

Conclusion: Our results showed a younger age at diagnosis and a higher incidence of cancer at the rectal site compared to the Western literature, as well as a high frequency of patients who presented with late-stage disease and other characteristics. However, larger multicenter studies are still needed to confirm our results.

2017 年至 2019 年摩洛哥北部结直肠癌的流行病学和解剖病理学概况。
背景和研究目的:结直肠癌(CRC)是全球第三大常见癌症类型,也是癌症相关死亡的第二大原因。在许多国家,结直肠癌都是一个重大的公共卫生问题,其发病率在全球范围内呈上升趋势。在摩洛哥,CRC 是第三大常见癌症。然而,摩洛哥(尤其是北部地区)有关 CRC 的流行病学数据非常有限。本研究旨在描述摩洛哥北部地区 CRC 的流行病学和临床病理学特征:这项回顾性研究于 2017 年 4 月至 2019 年 12 月期间在丹吉尔艾哈迈德-本-扎耶德-阿勒纳哈扬地区肿瘤中心进行。数据来自确诊的 CRC 患者的病历,并使用 SPSS 计算机软件 23 版进行分析:142名患者被确诊为CRC,占研究期间该中心发现的所有癌症患者的13.0%。所有患者的性别比例(男/女)为 1.1。平均年龄为 58 岁,60-69 岁的患者最多(占 29.0%)。与左右结肠相比,直肠是最常见的解剖部位(44.0%)。组织学上,腺癌是最常见的类型(91.3%),半数肿瘤为中度分化,只有 4.9% 的患者为分化不良肿瘤。确诊时,83.0%的患者已处于晚期(III 期或 IV 期),其中 40.3%的患者已出现转移性疾病。在我们的系列研究中,肝脏(64.8%)是受转移影响最大的部位。11.9%的患者出现复发:我们的研究结果表明,与西方文献相比,直肠癌的确诊年龄更小、发病率更高,而且出现晚期疾病和其他特征的患者比例较高。然而,我们仍需要更大规模的多中心研究来证实我们的结果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Arab Journal of Gastroenterology
Arab Journal of Gastroenterology Medicine-Gastroenterology
CiteScore
2.70
自引率
0.00%
发文量
52
期刊介绍: Arab Journal of Gastroenterology (AJG) publishes different studies related to the digestive system. It aims to be the foremost scientific peer reviewed journal encompassing diverse studies related to the digestive system and its disorders, and serving the Pan-Arab and wider community working on gastrointestinal disorders.
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