Lung enteric-type adenocarcinoma with gastric metastasis: a rare case report and literature review.

IF 5.7 2区医学 Q1 IMMUNOLOGY

Frontiers in Immunology Pub Date : 2024-10-23 eCollection Date: 2024-01-01 DOI:10.3389/fimmu.2024.1486214

Xiaoning Li, Kewei Ma, Xiaobo Ma, Xiangye Zhao, Mengge Fan, Yinghui Xu

引用次数: 0

Abstract

Lung enteric-type adenocarcinoma (ETAC) is a rare subtype of non-small cell lung cancer (NSCLC), comprising approximately 0.6% of all primary lung adenocarcinomas. It is characterized by a tendency for early metastasis and a prognosis comparable to that of common lung adenocarcinoma. This case report described a patient with lung-ETAC who developed gastric metastasis. The patient underwent treatment with chemotherapy and a PD-1 inhibitor, resulting in disease remission with a progression-free survival (PFS) of 8 months. The follow-up time was 13 months. This case report was aimed to enhance understanding of the biological behavior of this rare tumor and provide insights into potential future treatment strategies.

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伴有胃转移的肺肠型腺癌：一例罕见病例报告和文献综述。

肺肠型腺癌（ETAC）是非小细胞肺癌（NSCLC）的一种罕见亚型，约占所有原发性肺腺癌的 0.6%。其特点是容易早期转移，预后与普通肺腺癌相当。本病例报告描述了一名发生胃转移的肺ETAC患者。患者接受了化疗和PD-1抑制剂治疗，疾病得到缓解，无进展生存期（PFS）为8个月。随访时间为 13 个月。本病例报告旨在加深对这种罕见肿瘤生物学行为的了解，并为未来潜在的治疗策略提供见解。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Frontiers in Immunology IMMUNOLOGY-

CiteScore

9.80

自引率

11.00%

发文量

7153

审稿时长

14 weeks

期刊介绍： Frontiers in Immunology is a leading journal in its field, publishing rigorously peer-reviewed research across basic, translational and clinical immunology. This multidisciplinary open-access journal is at the forefront of disseminating and communicating scientific knowledge and impactful discoveries to researchers, academics, clinicians and the public worldwide. Frontiers in Immunology is the official Journal of the International Union of Immunological Societies (IUIS). Encompassing the entire field of Immunology, this journal welcomes papers that investigate basic mechanisms of immune system development and function, with a particular emphasis given to the description of the clinical and immunological phenotype of human immune disorders, and on the definition of their molecular basis.