Developing multiple EGFR-mutant lung cancers

IF 32.4 1区材料科学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Energy & Environmental Science Pub Date : 2024-11-06 DOI:10.1038/s41568-024-00773-9

Daniela Senft

引用次数: 0

Abstract

The occurrence of multiple independent tumours in patients with EGFR-mutant lung cancer was unexplained. A recent study in Nature Cancer identified distinct genetic predisposition mechanisms, including developmental mosaicism and germline EGFR variants, that contribute to the formation of multiple primary tumours.

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出现多种表皮生长因子受体突变肺癌

表皮生长因子受体突变型肺癌患者出现多个独立肿瘤的原因不明。最近发表在《自然-癌症》（Nature Cancer）杂志上的一项研究确定了不同的遗传易感机制，包括发育嵌合和种系表皮生长因子受体变异，这些都是形成多个原发性肿瘤的原因。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Energy & Environmental Science 化学-工程：化工

CiteScore

50.50

自引率

2.20%

发文量

349

审稿时长

2.2 months

期刊介绍： Energy & Environmental Science, a peer-reviewed scientific journal, publishes original research and review articles covering interdisciplinary topics in the (bio)chemical and (bio)physical sciences, as well as chemical engineering disciplines. Published monthly by the Royal Society of Chemistry (RSC), a not-for-profit publisher, Energy & Environmental Science is recognized as a leading journal. It boasts an impressive impact factor of 8.500 as of 2009, ranking 8th among 140 journals in the category "Chemistry, Multidisciplinary," second among 71 journals in "Energy & Fuels," second among 128 journals in "Engineering, Chemical," and first among 181 scientific journals in "Environmental Sciences." Energy & Environmental Science publishes various types of articles, including Research Papers (original scientific work), Review Articles, Perspectives, and Minireviews (feature review-type articles of broad interest), Communications (original scientific work of an urgent nature), Opinions (personal, often speculative viewpoints or hypotheses on current topics), and Analysis Articles (in-depth examination of energy-related issues).