Structural Elucidation and Complete NMR Spectral Assignments of Monascus Monacolin Analogs.

IF 1.9 3区 化学 Q3 CHEMISTRY, MULTIDISCIPLINARY
Jiachen Liu, Qingjiang Xu, Xin Wang, Ronghua Pan, Lizhong Zheng, Yonghong Zhang, Xiaoya Shang, Nan Wang
{"title":"Structural Elucidation and Complete NMR Spectral Assignments of Monascus Monacolin Analogs.","authors":"Jiachen Liu, Qingjiang Xu, Xin Wang, Ronghua Pan, Lizhong Zheng, Yonghong Zhang, Xiaoya Shang, Nan Wang","doi":"10.1002/mrc.5489","DOIUrl":null,"url":null,"abstract":"<p><p>One new monacolin analog, monacolin V (1), together with two new monacolin-like natural products, 6-hydroxyl monacolin P (2) and 3-keto monacolin S (3), were isolated from the ethyl acetate portion of red yeast rice ethanol extract. Their structures were identified by HRESIMS and NMR experiments, and the complete assignments of <sup>1</sup>H and <sup>13</sup>C NMR data for three compounds were obtained by the aid of HSQC, HMBC, <sup>1</sup>H-<sup>1</sup>H COSY, and NOESY data. This is the first time that the NMR data of compounds 2 and 3 have been fully assigned.</p>","PeriodicalId":18142,"journal":{"name":"Magnetic Resonance in Chemistry","volume":" ","pages":""},"PeriodicalIF":1.9000,"publicationDate":"2024-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Magnetic Resonance in Chemistry","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.1002/mrc.5489","RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0

Abstract

One new monacolin analog, monacolin V (1), together with two new monacolin-like natural products, 6-hydroxyl monacolin P (2) and 3-keto monacolin S (3), were isolated from the ethyl acetate portion of red yeast rice ethanol extract. Their structures were identified by HRESIMS and NMR experiments, and the complete assignments of 1H and 13C NMR data for three compounds were obtained by the aid of HSQC, HMBC, 1H-1H COSY, and NOESY data. This is the first time that the NMR data of compounds 2 and 3 have been fully assigned.

Monascus Monacolin 类似物的结构阐释和完整 NMR 光谱分配。
从红曲米乙醇提取物的乙酸乙酯部分中分离出了一种新的独活素类似物--独活素 V(1),以及两种新的独活素类天然产物--6-羟基独活素 P(2)和 3-酮独活素 S(3)。借助 HSQC、HMBC、1H-1H COSY 和 NOESY 数据,对三种化合物的 1H 和 13C NMR 数据进行了完整的分配。这是首次对化合物 2 和 3 的核磁共振数据进行完整的赋值。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
CiteScore
4.70
自引率
10.00%
发文量
99
审稿时长
1 months
期刊介绍: MRC is devoted to the rapid publication of papers which are concerned with the development of magnetic resonance techniques, or in which the application of such techniques plays a pivotal part. Contributions from scientists working in all areas of NMR, ESR and NQR are invited, and papers describing applications in all branches of chemistry, structural biology and materials chemistry are published. The journal is of particular interest not only to scientists working in academic research, but also those working in commercial organisations who need to keep up-to-date with the latest practical applications of magnetic resonance techniques.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信