[Ferroptosis:Mechanisms and Application in Tumor Treatment].

Q4 Medicine

中国医学科学院学报 Pub Date : 2024-10-01 DOI:10.3881/j.issn.1000-503X.15881

Shi-Han Shao, Shu-Ting Qiu, Yu Li, Ying-Ying Zhang, Yue-Jia Cao, Chun-Hong DI, Xiao-Hua Tan

引用次数: 0

Abstract

Ferroptosis is a form of regulated cell death that depends on iron and reactive oxygen species.Different from apoptosis,necrosis,and autophagy,ferroptosis is characterized by the accumulation of lipid peroxides in cells.Studies have discovered that ferroptosis is closely associated with the occurrence and development of tumors and inducing ferroptosis in tumor cells can enhance the therapeutic effects of drugs on tumors.This article summarizes the latest research progress in ferroptosis regarding its mechanisms and associations with tumors,aiming to provide a reference for further understanding the interaction mechanisms between ferroptosis and tumors and offering new insights and targets for the treatment of tumors.

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[铁蜕变：机制及在肿瘤治疗中的应用]。

研究发现，铁凋亡与肿瘤的发生和发展密切相关，诱导肿瘤细胞铁凋亡可增强药物对肿瘤的治疗效果。本文总结了有关铁氧化机制及其与肿瘤关系的最新研究进展，旨在为进一步了解铁氧化与肿瘤的相互作用机制提供参考，并为肿瘤治疗提供新的见解和靶点。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

中国医学科学院学报 Medicine-Medicine (all)

CiteScore

0.60

自引率

0.00%

发文量

6813

期刊介绍： Acta Academiae Medicinae Sinicae was founded in February 1979. It is a comprehensive medical academic journal published in China and abroad, supervised by the Ministry of Health of the People's Republic of China and sponsored by the Chinese Academy of Medical Sciences and Peking Union Medical College. The journal mainly reports the latest research results, work progress and dynamics in the fields of basic medicine, clinical medicine, pharmacy, preventive medicine, biomedicine, medical teaching and research, aiming to promote the exchange of medical information and improve the academic level of medicine. At present, the journal has been included in 10 famous foreign retrieval systems and their databases [Medline (PubMed online version), Elsevier, EMBASE, CA, WPRIM, ExtraMED, IC, JST, UPD and EBSCO-ASP]; and has been included in important domestic retrieval systems and databases [China Science Citation Database (Documentation and Information Center of the Chinese Academy of Sciences), China Core Journals Overview (Peking University Library), China Science and Technology Paper Statistical Source Database (China Science and Technology Core Journals) (China Institute of Scientific and Technological Information), China Science and Technology Journal Paper and Citation Database (China Institute of Scientific and Technological Information)].